TNFSF4 Protein (AA 51-183) (Fc Tag)

N° du produit ABIN6253372

Détail du produit

Antigène: TNFSF4 (Tumor Necrosis Factor (Ligand) Superfamily, Member 4 (TNFSF4))

Type de proteíne: Recombinant

Attributs du protein: AA 51-183

Origine: Humain, Souris

Source: HEK-293 Cells

Purification/Conjugué: Cette TNFSF4 protéine est marqué à la Fc Tag.

Fonction: CD252 [OX40L] (human):Fc (mouse) (rec.)

Specificité: The extracellular domain of human CD252 (aa 51-183) is fused to the N-terminus of the Fc region of mouse IgG2a.

Attributs du produit: Protein. The extracellular domain of human CD252 (aa 51-183) is fused to the N-terminus of the Fc region of mouse IgG2a. Source: HEK 293 cells. Endotoxin content: <5EU/mg purified protein (LAL test, Lonza). Lyophilized from 0.2μm-filtered solution in PBS. Purity: >98 % (SDS-PAGE). OX40L is a membrane-expressed cytokine that belongs to the TNF ligand family. It acts as costimulator through interaction with its ligand OX40 on T cells, stimulating T cell activation, proliferation and cytokine production. OX40L is expressed on antigen presenting cells including B cells, dendritic cells, mast cells and endothelium.

Pureté: >98 % (SDS-PAGE)

niveau d'endotoxine: <5EU/mg purified protein (LAL test, Lonza).

Biological Activity Comment: Measured by its binding ability in a functional ELISA.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized from 0.2μm-filtered solution in PBS.

Conseil sur la manipulation: Avoid freeze/thaw cycles.

Stock: 4 °C,-20 °C

Stockage commentaire:

Short Term Storage: +4°C

Long Term Storage: -20°C

Use & Stability: Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.

Détail du antigène

Antigène: TNFSF4 (Tumor Necrosis Factor (Ligand) Superfamily, Member 4 (TNFSF4))

Autre désignation: CD252 [OX40L] (TNFSF4 Produits)

Synonymes: TNFSF4 Protein, OX40L Protein, TNFRSF4 Protein, CD134L Protein, CD252 Protein, GP34 Protein, OX-40L Protein, OX4OL Protein, TXGP1 Protein, Ath-1 Protein, Ath1 Protein, Ox40l Protein, Txgp1l Protein, gp34 Protein, TNF superfamily member 4 Protein, tumor necrosis factor (ligand) superfamily, member 4 Protein, TNFSF4 Protein, Tnfsf4 Protein

Sujet:

Alternate Names/Synonyms: TNFSF4

Product Description: OX40L is a membrane-expressed cytokine that belongs to the TNF ligand family. It acts as costimulator through interaction with its ligand OX40 on T cells, stimulating T cell activation, proliferation and cytokine production. OX40L is expressed on antigen presenting cells including B cells, dendritic cells, mast cells and endothelium.

Poids moléculaire: ~55kDa (SDS-PAGE)

NCBI Accession: NP_003317

Pathways: Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Activated T Cell Proliferation, Cancer Immune Checkpoints