Prolactin Protein (PRL) (AA 29-227) (Fc Tag)
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- Antigène Voir toutes Prolactin (PRL) Protéines
- Prolactin (PRL)
- Type de proteíne
- Recombinant
- Attributs du protein
- AA 29-227
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Origine
- Humain
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Source
- HEK-293 Cells
- Purification/Conjugué
- Cette Prolactin protéine est marqué à la Fc Tag.
- Séquence
- AA 29-227
- Pureté
- >95 % as determined by SDS-PAGE.
- niveau d'endotoxine
- Less than 0.1 EU per μg by the LAL method.
- Top Product
- Discover our top product PRL Protéine
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- Tris with Glycine, Arginine and NaCl, pH 7.5
- Conseil sur la manipulation
- Please avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
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- Antigène
- Prolactin (PRL)
- Autre désignation
- Prolactin (PRL Produits)
- Synonymes
- PRL Protein, prolactin Protein, PRLB Protein, PRLSD1 Protein, Prl1a1 Protein, Prol Protein, RATPRLSD1 Protein, RNPROL Protein, AV290867 Protein, prl Protein, prolactin Protein, prolactin, gene 2 L homeolog Protein, PROLACTIN protein Protein, prolactin-like Protein, PRL Protein, prl.2.L Protein, Prl Protein, LOC100136792 Protein, LOC100136580 Protein, PROLACTIN Protein, LOC101843376 Protein
- Sujet
- Prolactin (gene name PRL) is a secreted neuroendocrine pituitary hormone that acts primarily on the mammary gland to promote lactation, but has pleiotropic effects in both males and females. Prolactin is synthesized as a prohormone. Following cleavage of the signal peptide, the length of the mature hormone is between 194 and 199 amino acids, depending on species. Hormone structure is stabilized by three intramolecular disulfide bonds. Excessive secretion of prolactin - hyperprolactinemia - is a relative common disorder in humans. This condition has numerous causes, including prolactin-secreting tumors and therapy with certain drugs. The prolactin receptor (gene name PRLR) is a transmembrane type I glycoprotein that belongs to the cytokine hematopoietic receptor family. Expression of the prolactin receptor is widespread. Each prolactin molecule is thought to bind two receptor molecules
- Poids moléculaire
- 49.8 kDa
- NCBI Accession
- NP_000939
- Pathways
- Signalistation JAK/STAT, Peptide Hormone Metabolism, Response to Growth Hormone Stimulus, Protein targeting to Nucleus
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