TNFSF4 Protein (AA 51-183) (Fc Tag)
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- Antigène Voir toutes TNFSF4 Protéines
- TNFSF4 (Tumor Necrosis Factor (Ligand) Superfamily, Member 4 (TNFSF4))
- Type de proteíne
- Recombinant
- Activité biologique
- Active
- Attributs du protein
- AA 51-183
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Origine
- Macaque rhésus
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Source
- HEK-293 Cells
- Purification/Conjugué
- Cette TNFSF4 protéine est marqué à la Fc Tag.
- Séquence
- AA 51-183
- Pureté
- >90 % as determined by SDS-PAGE.
- niveau d'endotoxine
- Less than 0.1 EU per μg by the LAL method.
- Top Product
- Discover our top product TNFSF4 Protéine
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- 50 mM Tris, 100 mM Glycine, pH 7.5
- Conseil sur la manipulation
- Please avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
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- Antigène
- TNFSF4 (Tumor Necrosis Factor (Ligand) Superfamily, Member 4 (TNFSF4))
- Autre désignation
- OX40 Ligand (TNFSF4 Produits)
- Synonymes
- TNFSF4 Protein, OX40L Protein, TNFRSF4 Protein, CD134L Protein, CD252 Protein, GP34 Protein, OX-40L Protein, OX4OL Protein, TXGP1 Protein, Ath-1 Protein, Ath1 Protein, Ox40l Protein, Txgp1l Protein, gp34 Protein, TNF superfamily member 4 Protein, tumor necrosis factor (ligand) superfamily, member 4 Protein, TNFSF4 Protein, Tnfsf4 Protein
- Sujet
- Tumor necrosis factor ligand superfamily member 4 (TNFSF4) is also known as glycoprotein Gp34, OX40 ligand (OX40L), TAX transcriptionally-activated glycoprotein 1 and CD252, which belongs to the tumor necrosis factor family. TNFSF4 is the ligand for CD134 and is expressed on such cells as DC2s (a subtype of dendritic cells) enabling amplification of Th2 cell differentiation. The interaction of TNFSF4-TNFSF4 is involved in the pathogenesis of multiple autoimmune and inflammatory diseases such as systemic lupus erythematosus (SLE), carotid artery disease and cancer. Furthermore, similar to other TNF superfamily members, membrane-bound OX40 Ligand (TNFSF4) exists as a homotrimer. Human TNFSF4 shares 46 % amino acid sequence identity with its mouse counterpart.
- Poids moléculaire
- 42.5 kDa
- NCBI Accession
- XP_017808006
- Pathways
- Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Activated T Cell Proliferation, Cancer Immune Checkpoints
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