PSMB10 Protein (AA 40-273) (His tag)
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- Antigène Voir toutes PSMB10 Protéines
- PSMB10 (Proteasome (Prosome, Macropain) Subunit, beta Type 10 (PSMB10))
- Type de proteíne
- Recombinant
- Attributs du protein
- AA 40-273
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Origine
- Humain
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Source
- Escherichia coli (E. coli)
- Purification/Conjugué
- Cette PSMB10 protéine est marqué à la His tag.
- Application
- SDS-PAGE (SDS)
- Attributs du produit
- PSMB10, 40-273aa, Human, His tag, E.coli
- Pureté
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product PSMB10 Protéine
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.25 mg/ml (determined by Bradford assay)
- Buffer
- Liquid. 20mM Tris-HCl buffer (pH8.0) containing 40% glycerol, 0.1M NaCl
- Stock
- 4 °C
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- Antigène
- PSMB10 (Proteasome (Prosome, Macropain) Subunit, beta Type 10 (PSMB10))
- Autre désignation
- PSMB10 (PSMB10 Produits)
- Sujet
- PSMB10 is a member of the proteasome B-type family, also known as the T1B family, which is a 20S core beta subunit. The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. Expression of the PSMB10 gene is induced by gamma interferon, and PSMB10 replaces catalytic subunit 2 (proteasome beta 7 subunit) in the immunoproteasome. Recombinant human PSMB10 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. Synonyms: Proteasome subunit beta type-10, LMP10, MECL1. NCBI no.: NP_002792
- Poids moléculaire
- 26.9 kDa (255aa), confirmed by MALDI-TOF
- Pathways
- Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA
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