BCL7A Protein (His tag)
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- Antigène Voir toutes BCL7A Protéines
- BCL7A (B-Cell CLL/lymphoma 7A (BCL7A))
- Type de proteíne
- Recombinant
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Origine
- Humain
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Source
- Escherichia coli (E. coli)
- Purification/Conjugué
- Cette BCL7A protéine est marqué à la His tag.
- Application
- SDS-PAGE (SDS)
- Purification
- purified by chromatography
- Pureté
- > 85 % by SDS - PAGE
- Top Product
- Discover our top product BCL7A Protéine
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- Commentaires
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Synonyms: B-cell CLL/lymphoma 7 protein family member A, BCL7
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.25 mg/ml (determined by Bradford assay)
- Buffer
- 20 mM Tris-HCl buffer (pH 8.0) containing 0.15 M NaCl, 10% glycerol, 1 MM DTT, 2 mM EDTA
- Stock
- 4 °C
- Stockage commentaire
- Avoid repeated freezing and thawing cycles.
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- Antigène
- BCL7A (B-Cell CLL/lymphoma 7A (BCL7A))
- Autre désignation
- BCL7A (BCL7A Produits)
- Synonymes
- BCL7 Protein, cb585 Protein, id:ibd1097 Protein, sb:cb585 Protein, wu:fk02d01 Protein, zgc:92023 Protein, 4432415N06Rik Protein, AI448316 Protein, bcl7a Protein, MGC89576 Protein, BCL7A Protein, BCL tumor suppressor 7A Protein, B-cell CLL/lymphoma 7A Protein, B cell CLL/lymphoma 7A Protein, B-cell CLL/lymphoma 7A L homeolog Protein, BCL7A Protein, bcl7a Protein, Bcl7a Protein, bcl7a.L Protein
- Sujet
- BCL7A is directly involved, with Myc and IgH, in a three-way gene translocation in a Burkitt lymphoma cell line. As a result of the gene translocation, the N-terminal region of the gene is disrupted, which is thought to be related to the pathogenesis of a subset of high-grade B cell non-Hodgkin lymphoma. The N-terminal segment involved in the translocation includes the region that shares a strong sequence similarity with those of BCL7B and BCL7C. Two transcript variants encoding different isoforms have been found for this gene. Recombinant human BCL7A protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
- Poids moléculaire
- 25.2 kDa (233aa), confirmed by MALDI-TOF (Molecular size on SDS-PAGE will appear higher)
- NCBI Accession
- NP_001019979
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