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SLAMF1 Protein (His tag)

SLAMF1 Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant > 85 % by SDS - PAGE SDS
N° du produit ABIN6387103
  • Antigène Voir toutes SLAMF1 Protéines
    SLAMF1 (Signaling Lymphocytic Activation Molecule Family Member 1 (SLAMF1))
    Type de proteíne
    Recombinant
    Origine
    • 12
    • 4
    • 3
    • 1
    Humain
    Source
    • 8
    • 4
    • 4
    • 2
    • 1
    Escherichia coli (E. coli)
    Purification/Conjugué
    Cette SLAMF1 protéine est marqué à la His tag.
    Application
    SDS-PAGE (SDS)
    Pureté
    > 85 % by SDS - PAGE
    Top Product
    Discover our top product SLAMF1 Protéine
  • Commentaires

    Synonyms: signaling lymphocytic activation molecule precursor, CD150, CDw150, SLAM

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.5 mg/ml (determined by Bradford assay)
    Buffer
    20 mM Tris-HCl buffer (pH 8.0) containing 0.4 M UREA, 10% glycerol
    Stock
    4 °C
    Stockage commentaire
    Avoid repeated freezing and thawing cycles.
  • Antigène
    SLAMF1 (Signaling Lymphocytic Activation Molecule Family Member 1 (SLAMF1))
    Autre désignation
    SLAMF1 (SLAMF1 Produits)
    Synonymes
    CD150 Protein, SLAM Protein, SLAMF1 Protein, 4933415F16 Protein, AA177906 Protein, CDw150 Protein, ESTM51 Protein, IPO-3 Protein, Slam Protein, RGD1560634 Protein, signaling lymphocytic activation molecule family member 1 Protein, SLAMF1 Protein, Slamf1 Protein
    Sujet
    SLAMF1 belongs to the immunoglobulin gene superfamily and is involved in T-cell stimulation. This protein is constitutively expressed on peripheral blood memory T cells, T-cell clones, immature thymocytes, and a proportion of B cells, and is rapidly induced on naive T cells after activation. High-affinity for self-ligand is important in bidirectional T-cell to B-cell stimulation. SLAM-induced signal-transduction events in T-lymphocytes are different from those in B-cells. Two modes of SLAM signaling are likely to exist: one in which the inhibitor SH2D1A acts as a negative regulator and another in which protein-tyrosine phosphatase 2C (PTPN11)-dependent signal transduction operates. Recombinant human SLAMF1 protein, fused to His-tag at N-terminus, was expressed in E.coli.
    Poids moléculaire
    26.7kDa (240aa)
    NCBI Accession
    NP_003028
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