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ORC6 Protein (AA 1-252) (His tag)
ORC6
Origine: Humain
Hôte: Escherichia coli (E. coli)
Recombinant
> 90 % by SDS - PAGE
SDS
N° du produit ABIN6387302
Détail du produit
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Antigène
Voir toutes ORC6 Protéines
ORC6
(Origin Recognition Complex, Subunit 6 (ORC6))
Type de proteíne
Recombinant
Attributs du protein
AA 1-252
Origine
Toutes les origines à travers ORC6 Protéines
Humain
Source
Toutes les sources à travers ORC6 Protéines
Escherichia coli (E. coli)
Purification/Conjugué
Cette ORC6 protéine est marqué à la His tag.
Application
SDS-PAGE (SDS)
Séquence
MGSSHHHHHH SSGLVPRGSH MGSMGSELIG RLAPRLGLAE PDMLRKAEEY LRLSRVKCVG LSARTTETSS AVMCLDLAAS WMKCPLDRAY LIKLSGLNKE TYQSCLKSFE CLLGLNSNIG IRDLAVQFSC IEAVNMASKI LKSYESSLPQ TQQVDLDLSR PLFTSAALLS ACKILKLKVD KNKMVATSGV KKAIFDRLCK QLEKIGQQVD REPGDVATPP RKRKKIVVEA PAKEMEKVEE MPHKPQKDED LTQDYEEWKR KILENAASAQ KATAE
Pureté
> 90 % by SDS - PAGE
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Information d'application
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Indications d'application
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Stockage
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Format
Liquid
Concentration
0.25 mg/mL
Buffer
Liquid. In 20 mM Tris-HCl buffer ( pH 8.0) containing 0.2M NaCl, 40 % glycerol, 2 mM DTT
Stock
4 °C,-20 °C,-80 °C
Stockage commentaire
Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
Détail du antigène
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Antigène
ORC6
(Origin Recognition Complex, Subunit 6 (ORC6))
Autre désignation
ORC6 (ORC6 Produits )
Synonymes
Orc6l Protein, CG1584 Protein, DmORC 6 Protein, DmORC6 Protein, Dmel\\CG1584 Protein, ORC Protein, ORC6 Protein, orc6 Protein, rDmORC Protein, ORC6L Protein, ARABIDOPSIS THALIANA ORIGIN RECOGNITION COMPLEX PROTEIN 6 Protein, ATORC6 Protein, ORIGIN RECOGNITION COMPLEX SUBUNIT 6 Protein, T2P11.3 Protein, T2P11_3 Protein, origin recognition complex protein 6 Protein, DDBDRAFT_0186183 Protein, DDBDRAFT_0233113 Protein, DDB_0186183 Protein, DDB_0233113 Protein, LOC100284755 Protein, orc6l Protein, 6720420I10Rik Protein, origin recognition complex, subunit 6 Protein, Origin recognition complex subunit 6 Protein, origin recognition complex subunit 6 Protein, origin recognition complex protein 6 Protein, origin recognition complex subunit Orc6 Protein, Orc6 Protein, ORC6 Protein, CpipJ_CPIJ005016 Protein, SJAG_01267 Protein, orcF Protein, LOC100284755 Protein, orc6 Protein
Sujet
Origin recognition complex subunit 6, also known as ORC6, belongs to the origin recognition complex (ORC). ORC is a highly conserved heterohexameric protein complex that associates with DNA at or near sites of initiation of DNA replication. All six ORC subunits are essential for initiation of DNA replication, and ORC may be involved in regulation of gene expression in response to stress. ORC6 is also expressed constantly throughout the cell cycle. ORC2, ORC3, ORC4 and ORC5 form a core complex upon which ORC6 and ORC1 assemble. Recombinant human ORC6 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
Poids moléculaire
30.5 kDa (275aa) confirmed by MALDI-TOF
NCBI Accession
NP_055136
UniProt
Q9Y5N6
Pathways
Mitotic G1-G1/S Phases , DNA Replication , M Phase , Synthesis of DNA
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