GDI2 Protein (AA 1-445) (His tag)

N° du produit ABIN6387420

Détail du produit

Antigène: GDI2 (GDP Dissociation Inhibitor 2 (GDI2))

Type de proteíne: Recombinant

Attributs du protein: AA 1-445

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette GDI2 protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Séquence: MGSSHHHHHH SSGLVPRGSH MGSMNEEYDV IVLGTGLTEC ILSGIMSVNG KKVLHMDRNP YYGGESASIT PLEDLYKRFK IPGSPPESMG RGRDWNVDLI PKFLMANGQL VKMLLYTEVT RYLDFKVTEG SFVYKGGKIY KVPSTEAEAL ASSLMGLFEK RRFRKFLVYV ANFDEKDPRT FEGIDPKKTT MRDVYKKFDL GQDVIDFTGH ALALYRTDDY LDQPCYETIN RIKLYSESLA RYGKSPYLYP LYGLGELPQG FARLSAIYGG TYMLNKPIEE IIVQNGKVIG VKSEGEIARC KQLICDPSYV KDRVEKVGQV IRVICILSHP IKNTNDANSC QIIIPQNQVN RKSDIYVCMI SFAHNVAAQG KYIAIVSTTV ETKEPEKEIR PALELLEPIE QKFVSISDLL VPKDLGTESQ IFISRTYDAT THFETTCDDI KNIYKRMTGS EFDFEEMKRK KNDIYGED

Pureté: > 85 % by SDS - PAGE

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Liquid. In 20  mM Tris-HCl buffer (  pH 8.0) containing 0.1M NaCl, 10 % glycerol, 1  mM DTT

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Détail du antigène

Antigène: GDI2 (GDP Dissociation Inhibitor 2 (GDI2))

Autre désignation: GDI2 (GDI2 Produits)

Synonymes: Gdi3 Protein, fc09e02 Protein, zgc:55919 Protein, zgc:77120 Protein, wu:fc09e02 Protein, GDI2 Protein, RABGDIB Protein, GDI-2 Protein, GDI-B Protein, GDIB Protein, GDP dissociation inhibitor 2 Protein, GDP dissociation inhibitor 1 S homeolog Protein, guanosine diphosphate (GDP) dissociation inhibitor 2 Protein, gdi2 Protein, GDI2 Protein, gdi1.S Protein, Gdi2 Protein

Sujet: Rab GDP dissociation inhibitor beta isoform 1, also known as GDI2, belongs to the GDP dissociation inhibitors (GDIs) family. GDIs can bind and release GDP-bound Rab proteins from membranes. Two GDI proteins towards different Rab proteins have been identified. GDI1 interacts with almost all of the Rab proteins, while GDI2 interacts with Rabll but not Rab3A. GDI2 distributes ubiquitously, displaying a membrane bound location in perinuclear regions of cells. GDI-2 was thought to be involved in cellular response to insulin. Recombinant human GDI2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Poids moléculaire: 53.1 kDa (468aa)

NCBI Accession: NP_001485

UniProt: P50395