MAP2K6 Protein (AA 53-314) (His tag)

N° du produit ABIN6387535

Détail du produit

Antigène: MAP2K6 (Mitogen-Activated Protein Kinase Kinase 6 (MAP2K6))

Type de proteíne: Recombinant

Attributs du protein: AA 53-314

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette MAP2K6 protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Séquence: MGSSHHHHHH SSGLVPRGSH MLEPIMELGR GAYGVVEKMR HVPSGQIMAV KRIRATVNSQ EQKRLLMDLD ISMRTVDCPF TVTFYGALFR EGDVWICMEL MDTSLDKFYK QVIDKGQTIP EDILGKIAVS IVKALEHLHS KLSVIHRDVK PSNVLINALG QVKMCDFGIS GYLVDEVAKE IDAGCKPYMA PERINPELNQ KGYSVKSDIW SLGITMIELA ILRFPYDSWG TPFQQLKQVV EEPSPQLPAD KFSAEFVDFT SQCLKKNSKE RPTYPELMQH PFF

Pureté: > 85 % by SDS - PAGE

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

Denatured

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: Liquid, In 20  mM Tris-HCl (  pH 8.0) containing 10 % glycerol

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles

Détail du antigène

Antigène: MAP2K6 (Mitogen-Activated Protein Kinase Kinase 6 (MAP2K6))

Autre désignation: MAP2K6 (MAP2K6 Produits)

Synonymes: MAPKK6 Protein, MEK6 Protein, MKK6 Protein, PRKMK6 Protein, SAPKK-3 Protein, SAPKK3 Protein, Mkk6 Protein, Prkmk6 Protein, MKK3 Protein, map2k3 Protein, zMKK3 Protein, map2k6 Protein, mitogen-activated protein kinase kinase 6 Protein, mitogen-activated protein kinase kinase 6 L homeolog Protein, MAP2K6 Protein, Map2k6 Protein, map2k6 Protein, map2k6.L Protein

Sujet: MAP2K6 is a member of the dual specificity protein kinase family, which functions as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein phosphorylates and activates p38 MAP kinase in response to inflammatory cytokines or environmental stress. As an essential component of p38 MAP kinase mediated signal transduction pathway, MAP2K6 is involved in many cellular processes such as stress induced cell cycle arrest, transcription activation and apoptosis. Recombinant human MAP2K6, fused to His-tag at N-terminus, was expressed in E.coli.

Poids moléculaire: 32.0 kDa (383aa)

NCBI Accession: NP_002749

UniProt: P52564

Pathways: Signalisation MAPK, Signalisation TLR, Activation of Innate immune Response, Regulation of Muscle Cell Differentiation, Toll-Like Receptors Cascades