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DCXR Protein (AA 1-244) (His tag)

DCXR Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant > 95 % by SDS - PAGE SDS Active
N° du produit ABIN6387971
  • Antigène Voir toutes DCXR Protéines
    DCXR (Dicarbonyl/L-Xylulose Reductase (DCXR))
    Type de proteíne
    Recombinant
    Activité biologique
    Active
    Attributs du protein
    AA 1-244
    Origine
    • 8
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Source
    • 5
    • 5
    • 2
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification/Conjugué
    Cette DCXR protéine est marqué à la His tag.
    Application
    SDS-PAGE (SDS)
    Séquence
    MGSSHHHHHH SSGLVPRGSH MELFLAGRRV LVTGAGKGIG RGTVQALHAT GARVVAVSRT QADLDSLVRE CPGIEPVCVD LGDWEATERA LGSVGPVDLL VNNAAVALLQ PFLEVTKEAF DRSFEVNLRA VIQVSQIVAR GLIARGVPGA IVNVSSQCSQ RAVTNHSVYC STKGALDMLT KVMALELGPH KIRVNAVNPT VVMTSMGQAT WSDPHKAKTM LNRIPLGKFA EVEHVVNAIL FLLSDRSGMT TGSTLPVEGG FWAC
    Pureté
    > 95 % by SDS - PAGE
    Biological Activity Comment
    Specific activity is > 1,800 pmol/min/ug and is defined as the amount of enzyme that oxidize 1pmole of xylitol to L-xylulose per minute at pH 10.0 at 37C.
    Top Product
    Discover our top product DCXR Protéine
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Commentaires

    Bioactivity Validated

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.5 mg/mL
    Buffer
    Liquid. In 20  mM Tris-HCl buffer (  pH 8.0) containing 1  mM DTT, 20 % glycerol, 50  mM NaCl
    Stock
    4 °C,-20 °C,-80 °C
    Stockage commentaire
    Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
  • Antigène
    DCXR (Dicarbonyl/L-Xylulose Reductase (DCXR))
    Autre désignation
    DCXR (DCXR Produits)
    Synonymes
    DCR Protein, HCR2 Protein, HCRII Protein, KIDCR Protein, P34H Protein, SDR20C1 Protein, XR Protein, dcxr Protein, DCXR Protein, DER Protein, 0610038K04Rik Protein, 1810027P18Rik Protein, glb Protein, wu:fa12f09 Protein, zgc:111977 Protein, GLB Protein, dicarbonyl and L-xylulose reductase Protein, dicarbonyl/L-xylulose reductase Protein, dicarbonyl L-xylulose reductase Protein, L-xylulose reductase Protein, L-xylulose reductase, putative Protein, dicarbonyl/L-xylulose reductase L homeolog Protein, DCXR Protein, dcxr Protein, Dcxr Protein, CNL05930 Protein, NCU09041 Protein, AOR_1_494194 Protein, VDBG_02657 Protein, CGB_D1070C Protein, dcxr.L Protein
    Sujet
    Dicarbonyl/L-xylulose reductase, also known as DCXR, is an enzyme responsible for the metabolism of xylulose, converting it into xylitol. DCXR was expressed at low levels and was localized predominantly in the cytoplasmic membrane. In contrast, in virtually all grades of early-stage prostate cancer and in all chemohormonally treated cases, DCXR was strikingly overexpressed and was localized predominantly in the cytoplasm and nucleus. Recombinant human DCXR, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
    Poids moléculaire
    28 kDa (264aa), confirmed by MALDI-TOF
    NCBI Accession
    NP_057370
    UniProt
    Q7Z4W1
    Pathways
    Glycosaminoglycan Metabolic Process, Monocarboxylic Acid Catabolic Process
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