Kallikrein 15 Protein (AA 17-256) (His tag)

N° du produit ABIN6388017

Détail du produit

Antigène: Kallikrein 15 (KLK15) (Kallikrein-Related Peptidase 15 (KLK15))

Type de proteíne: Recombinant

Attributs du protein: AA 17-256

Origine: Humain

Source: Baculovirus infected Insect Cells

Purification/Conjugué: Cette Kallikrein 15 protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Séquence: ADPQDGDKLL EGDECAPHSQ PWQVALYERG RFNCGASLIS PHWVLSAAHC QSRFMRVRLG EHNLRKRDGP EQLRTTSRVI PHPRYEARSH RNDIMLLRLV QPARLNPQVR PAVLPTRCPH PGEACVVSGW GLVSHNEPGT AGSPRSQVSL PDTLHCANIS IISDTSCDKS YPGRLTNTMV CAGAEGRGAE SCEGDSGGPL VCGGILQGIV SWGDVPCDNT TKPGVYTKVC HYLEWIRETM KRNHHHHHH

Pureté: > 80 % by SDS - PAGE

niveau d'endotoxine: < 1.0 EU per 1 microgram of protein (determined by LAL method)

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: Liquid. In Phosphate Buffered Saline (  pH 7.4) containing 10 % glycerol.

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Détail du antigène

Antigène: Kallikrein 15 (KLK15) (Kallikrein-Related Peptidase 15 (KLK15))

Autre désignation: KLK15 (KLK15 Produits)

Synonymes: ACO Protein, HSRNASPH Protein, kallikrein related-peptidase 15 Protein, kallikrein related peptidase 15 Protein, kallikrein-related peptidase 15 Protein, Klk15 Protein, KLK15 Protein

Sujet: KLK15, also known as kallikrein-15 isoform 4, is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. This protein contains multiple polyadenylation sites and alternative splicing results in multiple transcript variants encoding distinct isoforms. Also, growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. In prostate cancer, it has increased expression, which indicates its possible use as a diagnostic or prognostic marker for prostate cancer. Recombinant human KLK15, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Poids moléculaire: 27.4kDa (249aa) 28-40kDa (SDS-PAGE under reducing conditions.)

NCBI Accession: NP_059979

UniProt: Q9H2R5

Pathways: Système du Complément