PRKACA Protein (AA 1-351) (GST tag)

N° du produit ABIN6388022

Détail du produit

Antigène: PRKACA (Protein Kinase A, alpha (PRKACA))

Type de proteíne: Recombinant

Attributs du protein: AA 1-351

Origine: Humain

Source: Baculovirus infected Insect Cells

Purification/Conjugué: Cette PRKACA protéine est marqué à la GST tag.

Application: SDS-PAGE (SDS)

Séquence: MSPILGYWKI KGLVQPTRLL LEYLEEKYEE HLYERDEGDK WRNKKFELGL EFPNLPYYID GDVKLTQSMA IIRYIADKHN MLGGCPKERA EISMLEGAVL DIRYGVSRIA YSKDFETLKV DFLSKLPEML KMFEDRLCHK TYLNGDHVTH PDFMLYDALD VVLYMDPMCL DAFPKLVCFK KRIEAIPQID KYLKSSKYIA WPLQGWQATF GGGDHPPKSD LVPRGSHMGN AAAAKKGSEQ ESVKEFLAKA KEDFLKKWES PAQNTAHLDQ FERIKTLGTG SFGRVMLVKH KETGNHYAMK ILDKQKVVKL KQIEHTLNEK RILQAVNFPF LVKLEFSFKD NSNLYMVMEY VPGGEMFSHL RRIGRFSEPH ARFYAAQIVL TFEYLHSLDL IYRDLKPENL LIDQQGYIQV TDFGFAKRVK GRTWTLCGTP EYLAPEIILS KGYNKAVDWW ALGVLIYEMA AGYPPFFADQ PIQIYEKIVS GKVRFPSHFS SDLKDLLRNL LQVDLTKRFG NLKNGVNDIK NHKWFATTDW IAIYQRKVEA PFIPKFKGPG DTSNFDDYEE EEIRVSINEK CGKEFSEF

Pureté: > 85 % by SDS - PAGE

niveau d'endotoxine: < 1.0 EU per 1 microgram of protein (determined by LAL method)

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: Liquid. In Phosphate Buffered Saline (  pH 7.4) containing 10 % glycerol.

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Détail du antigène

Antigène: PRKACA (Protein Kinase A, alpha (PRKACA))

Autre désignation: PRKACA (PRKACA Produits)

Synonymes: PKACA Protein, Calpha Protein, Cs-PKA Protein, PKCA1 Protein, PKA Protein, PKCD Protein, Pkaca Protein, zgc:158799 Protein, protein kinase cAMP-activated catalytic subunit alpha Protein, protein kinase, cAMP dependent, catalytic, alpha Protein, cAMP-dependent protein kinase catalytic subunit Protein, protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate a Protein, PRKACA Protein, Prkaca Protein, kin-1 Protein, prkacaa Protein

Sujet: PRKACA, also known as cAMP-dependent protein kinase catalytic subunit alpha isoform Calpha1, is a member of the Ser/Thr protein kinase family. It is responsible for phosphorylating other proteins and substrates, changing their activity. This protein is a member of the AGC kinase family, and contributes to the control of cellular processes that include glucose metabolism, cell division, and contextual memory. Recombinant human PRKACA protein, fused to GST-tag at N-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Poids moléculaire: 67.0kDa (578aa) 50-70KDa (SDS-PAGE under reducing conditions.)

NCBI Accession: NP_002721

UniProt: P17612

Pathways: Signalisation NF-kappaB, Signalisation Hedgehog, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Thyroid Hormone Synthesis, Carbohydrate Homeostasis, Myometrial Relaxation and Contraction, M Phase, G-protein mediated Events, Signaling Events mediated by VEGFR1 and VEGFR2, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling, VEGFR1 Specific Signals, Lipid Metabolism, SARS-CoV-2 Protein Interactome, Phosphorylation & l'infection par le SRAS-CoV-2