MYDGF Protein (AA 25-166) (His tag)

N° du produit ABIN6388124

Détail du produit

Antigène: MYDGF (D17Wsu104e) (DNA segment, Chr 17, Wayne State University 104, expressed (D17Wsu104e))

Type de proteíne: Recombinant

Attributs du protein: AA 25-166

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette MYDGF protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Séquence: MGSSHHHHHH SSGLVPRGSH MGSVSEPTTV PFDVRPGGVV HSFSQDVGPG NKFTCTFTYA SQGGTNEQWQ MSLGTSEDSQ HFTCTIWRPQ GKSYLYFTQF KAELRGAEIE YAMAYSKAAF ERESDVPLKS EEFEVTKTAV SHRPGAFKAE LSKLVIVAKA ARSEL

Pureté: > 95 % by SDS - PAGE

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Liquid. In 20  mM Tris-HCl(  pH 8.0) containing 0.1M NaCl, 10 % glycerol

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Détail du antigène

Antigène: MYDGF (D17Wsu104e) (DNA segment, Chr 17, Wayne State University 104, expressed (D17Wsu104e))

Autre désignation: Mydgf (D17Wsu104e Produits)

Synonymes: EUROIMAGE1875335 Protein, IL25 Protein, IL27 Protein, IL27w Protein, R33729_1 Protein, SF20 Protein, Il25 Protein, Ly6elg Protein, myeloid derived growth factor Protein, MYDGF Protein, Mydgf Protein

Sujet: Mydgf, also known as Myeloid-derived growth factor, is a bone marrow-derived monocyte and paracrine-acting protein that promotes cardiac myocyte survival and adaptive angiogenesis for cardiac protection and repair after myocardial infarction. It stimulates endothelial cell proliferation through a MAPK1/3-, STAT3- and CCND1-mediated signaling pathway. Mydgf-deficient mice develop larger infarct scars and more severe contractile dysfunction compared to wild-type mice. Recombinant mouse Mydgf, fused to His-tag at N-termineus, was expressed in E. coli and purified by using conventional chromatography techniques.

Poids moléculaire: 18.1 kDa (165aa) Confirmed by MALDI-TOF

NCBI Accession: NP_543027

UniProt: Q9CPT4