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IL2 Receptor beta Protein (AA 27-239) (His tag)

IL2RB Origine: Humain Hôte: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE.
N° du produit ABIN6559943
  • Antigène Voir toutes IL2 Receptor beta (IL2RB) Protéines
    IL2 Receptor beta (IL2RB) (Interleukin 2 Receptor, beta (IL2RB))
    Type de proteíne
    Recombinant
    Attributs du protein
    AA 27-239
    Origine
    • 18
    • 10
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    Humain
    Source
    • 14
    • 8
    • 7
    • 4
    • 2
    • 1
    • 1
    HEK-293 Cells
    Purification/Conjugué
    Cette IL2 Receptor beta protéine est marqué à la His tag.
    Séquence
    AA 27-239
    Attributs du produit
    This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 25.4 kDa. The protein migrates as 40 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
    Pureté
    >90 % as determined by SDS-PAGE.
    Stérilité
    0.22 μm filtered
    niveau d'endotoxine
    Less than 1.0 EU per μg by the LAL method.
    Top Product
    Discover our top product IL2RB Protéine
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    PBS, pH 7.4
    Conseil sur la manipulation
    Please avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C-8 °C), After reconstitution under sterile conditions for 1 month (4 °C-8 °C) or 3 months (-20 °C to -70 °C).
  • Antigène
    IL2 Receptor beta (IL2RB) (Interleukin 2 Receptor, beta (IL2RB))
    Autre désignation
    IL-2 R beta (IL2RB Produits)
    Synonymes
    IL2RB Protein, il-2rb Protein, CD122 Protein, IL15RB Protein, P70-75 Protein, IL2RBC Protein, IL-15Rbeta Protein, IL15Rbeta Protein, Il-2/15Rbeta Protein, Il-2Rbeta Protein, p70 Protein, interleukin 2 receptor subunit beta Protein, interleukin-2 receptor subunit beta Protein, interleukin 2 receptor, beta Protein, interleukin 2 receptor, beta chain Protein, IL2RB Protein, LOC510185 Protein, il2rb Protein, Il2rb Protein
    Sujet
    Interleukin-2 receptor (IL-2R) is a heterotrimeric protein expressed on the surface of certain immune cells, such as lymphocytes, that binds and responds to a cytokine called IL-2. The IL-2R is made up of 3 subunits - α (CD25), β (CD122) and γ (CD132) - non-covalently associating. The α and β chains are involved in binding IL-2, while signal transduction following cytokine interaction is carried out by the γ-chain, along with the β subunit. CD122 is also known as IL2R beta, is a member of the type I cytokine receptor family. CD122 is the receptor for interleukin-2 and is involved in receptor mediated endocytosis and transduces the mitogenic signals of IL2.
    Poids moléculaire
    25.4 kDa
    NCBI Accession
    NP_000869
    Pathways
    Signalistation JAK/STAT, Growth Factor Binding
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