FOXO3 Protein (AA 372-673) (His-SUMO Tag)

N° du produit ABIN6653946

Détail du produit

Antigène: FOXO3 (Forkhead Box O3 (FOXO3))

Type de proteíne: Recombinant

Attributs du protein: AA 372-673

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette FOXO3 protéine est marqué à la His-SUMO Tag.

Séquence: MAGTMNLNDG LTENLMDDLL DNITLPPSQP SPTGGLMQRS SSFPYTTKGS GLGSPTSSFN STVFGPSSLN SLRQSPMQTI QENKPATFSS MSHYGNQTLQ DLLTSDSLSH SDVMMTQSDP LMSQASTAVS AQNSRRNVML RNDPMMSFAA QPNQGSLVNQ NLLHHQHQTQ GALGGSRALS NSVSNMGLSE SSSLGSAKHQ QQSPVSQSMQ TLSDSLSGSS LYSTSANLPV MGHEKFPSDL DLDMFNGSLE CDMESIIRSE LMDADGLDFN FDSLISTQNV VGLNVGNFTG AKQASSQSWV PG

Attributs du produit: N-terminal 6xHis-SUMO-tagged

Pureté: Greater than 85% as determined by SDS-PAGE.

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.1-2 mg/mL

Buffer: 20 mM Tris-HCl based buffer, pH 8.0

Stock: -80 °C,4 °C,-20 °C

Stockage commentaire: Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Détail du antigène

Antigène: FOXO3 (Forkhead Box O3 (FOXO3))

Autre désignation: FOXO3 (FOXO3 Produits)

Synonymes: AF6q21 Protein, FKHRL1 Protein, FKHRL1P2 Protein, FOXO2 Protein, FOXO3A Protein, zgc:92176 Protein, wu:fb50g02 Protein, wu:fi33f07 Protein, Fkhrl1 Protein, Foxo3a Protein, FoxO3A Protein, 1110048B16Rik Protein, 2010203A17Rik Protein, C76856 Protein, Fkhr2 Protein, FOXO-3 Protein, FOXO3 Protein, foxo3a Protein, xfoxo3 Protein, foxO3 Protein, foxO Protein, fkhr Protein, foxo5 Protein, wu:fj65a12 Protein, zFkhr Protein, forkhead box O3 Protein, forkhead box O3A Protein, forkhead box O3 L homeolog Protein, forkhead box O3b Protein, FOXO3 Protein, foxo3a Protein, Foxo3 Protein, foxo3.L Protein, foxo3 Protein, foxO3 Protein, foxo3b Protein

Sujet: Transcriptional activator which triggers apoptosis in the absence of survival factors, including neuronal cell death upon oxidative stress. Recognizes and binds to the DNA sequence 5'-[AG]TAAA[TC]A-3'. Participates in post-transcriptional regulation of MYC: following phosphorylation by MAPKAPK5, promotes induction of miR-34b and miR-34c expression, 2 post-transcriptional regulators of MYC that bind to the 3'UTR of MYC transcript and prevent its translation.

Poids moléculaire: 48.1 kDa

UniProt: O43524

Pathways: Cycle Cellulaire, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Carbohydrate Homeostasis