CDK2AP1 Protein (AA 1-115) (His tag)

N° du produit ABIN666944

Détail du produit

Antigène: CDK2AP1 (Cyclin-Dependent Kinase 2 Associated Protein 1 (CDK2AP1))

Type de proteíne: Recombinant

Attributs du protein: AA 1-115

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette CDK2AP1 protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Attributs du produit: CDK2AP1, 1-115aa, Human, His tag, E. coli

Pureté: > 95 % by SDS - PAGE

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/ml (determined by Bradford assay)

Buffer: Liquid. 20mM Tris-HCl buffer (pH8.0) containing 50% glycerol, 2mM DTT

Stock: 4 °C

Détail du antigène

Antigène: CDK2AP1 (Cyclin-Dependent Kinase 2 Associated Protein 1 (CDK2AP1))

Autre désignation: CDK2AP1 (CDK2AP1 Produits)

Synonymes: MGC64532 Protein, doc1 Protein, st19 Protein, doc-1 Protein, dorc1 Protein, p12doc-1 Protein, Apc10 Protein, Cdkap1 Protein, DORC1 Protein, Doc1 Protein, ST19 Protein, p12 Protein, DOC1 Protein, p12DOC-1 Protein, cyclin-dependent kinase 2 associated protein 1 S homeolog Protein, cyclin dependent kinase 2 associated protein 1 Protein, cyclin dependent kinase 2 associated protein 1 pseudogene Protein, cyclin-dependent kinase 2 associated protein 1 Protein, CDK2 (cyclin-dependent kinase 2)-associated protein 1 Protein, cdk2ap1.S Protein, CDK2AP1 Protein, LOC475806 Protein, cdk2ap1 Protein, Cdk2ap1 Protein

Sujet: CDK2AP1 is a specific CDK2-associated protein, which is thought to negatively regulate CDK2 activity by sequestering monomeric CDK2, and targeting CDK2 for proteolysis. Also, interact with DNA polymerase alpha/primase and mediate the phosphorylation of the large p180 subunit, which suggested the regulatory role in DNA replication during S phase of the cell cycle. A similar gene in hamster was isolated from, and functions as a growth suppressor of normal keratinocytes. Recombinant CDK2AP1 protein was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: CDKAP1, DOC1, CDKA1, Cyclin-dependent kinase 2 associated protein 1 CDK2 A1, CDK2 associated protein 1, CDK2AP1, Cyclin dependent kinase 2 associated protein 1 Deleted in oral cancer 1, DOC 1, DOC 1 related protein, DOC 1R, DOC1R, Putative oral cancer suppressor. NCBI no.: NP_004633

Poids moléculaire: 16.6kDa (152aa), confirmed by MALDI-TOF.