CACYBP Protein (AA 1-185) (His tag)

N° du produit ABIN667003

Détail du produit

Antigène: CACYBP (Calcyclin Binding Protein (CACYBP))

Type de proteíne: Recombinant

Attributs du protein: AA 1-185

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette CACYBP protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Attributs du produit: CACYBP, 1-185aa, Human, His tag, E.coli

Pureté: > 85 % by SDS-PAGE

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/ml (determined by Bradford assay)

Buffer: Liquid. In 20mM Tris-HCl buffer(pH 8.0) containing 10% glycerol, 1mM DTT, 0.1M NaCl.

Stock: 4 °C

Détail du antigène

Antigène: CACYBP (Calcyclin Binding Protein (CACYBP))

Autre désignation: CACYBP (CACYBP Produits)

Synonymes: zgc:76993 Protein, CACYBP Protein, sip Protein, gig5 Protein, pnas-107 Protein, s100a6bp Protein, T1P2.12 Protein, T1P2_12 Protein, GIG5 Protein, RP1-102G20.6 Protein, S100A6BP Protein, SIP Protein, calcyclin binding protein Protein, calcyclin binding protein, putative Protein, Calcyclin binding protein, putative Protein, SGS domain-containing protein Protein, calcyclin binding protein L homeolog Protein, cacybp Protein, CACYBP Protein, PB000926.02.0 Protein, PCHAS_145490 Protein, PVX_100855 Protein, PKH_145680 Protein, AT1G30070 Protein, cacybp.L Protein, Cacybp Protein

Sujet: CACYBP is primarily a nuclear protein that contains one CS domain and one SGS domain. It is believed to be involved in calcium-dependent ubiquitination and subsequent proteosomal degradation of target proteins. It most likely serves as a molecular bridge in Ubiquitin E3 complexes. It also participates in the Ubiquitin-mediated degradation of beta-catenin. CACYBP is thought to be a potential inhibitor of cell growth and invasion in the gastric cancer cell through its effects on beta-catenin protein expression and transcriptional activation of TCF/LEF. Recombinant human CACYBP protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: GIG5, PNAS-107, RP1-102G20.6, S100A6BP, SIP, Clcyclin-binding protein CACYBP, Calcyclin binding protein, GIG 5, Growth inhibiting gene 5, Growth inhibiting gene 5 protein, hCacyBP, MGC87971, PNAS 107, PNAS107, RP1 102G20.6, S100A6 binding protein. NCBI no.: NP_001007215

Poids moléculaire: 23.4 kDa (205aa), confirmed by MALDI-TOF

Pathways: Response to Growth Hormone Stimulus