PGAM1 Protein (AA 1-254) (His tag)

N° du produit ABIN667196

Détail du produit

Antigène: PGAM1 (phosphoglycerate Mutase 1 (Brain) (PGAM1))

Type de proteíne: Recombinant

Attributs du protein: AA 1-254

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette PGAM1 protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Attributs du produit: PGAM1, 1-254aa, Human, His tag, E.coli

Pureté: > 90 % by SDS – PAGE

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/ml (determined by Bradford assay)

Buffer: Liquid. In 20mM Tris-HCl buffer(pH 8.0) containing 10% glycerol, 1mM DTT

Stock: 4 °C

Détail du antigène

Antigène: PGAM1 (phosphoglycerate Mutase 1 (Brain) (PGAM1))

Autre désignation: PGAM1 (PGAM1 Produits)

Synonymes: PGAM-B Protein, PGAMA Protein, Pgmut Protein, MGC81450 Protein, 2310050F24Rik Protein, Pgam-1 Protein, pgam1 Protein, wu:fb81h05 Protein, fd15c02 Protein, pgam1lb Protein, wu:fd15c02 Protein, zgc:63722 Protein, phosphoglycerate mutase 1 Protein, phosphoglycerate mutase 1 L homeolog Protein, phosphoglycerate mutase 1a Protein, phosphoglycerate mutase 1b Protein, PGAM1 Protein, Pgam1 Protein, pgam1.L Protein, pgam1 Protein, pgam1a Protein, pgam1b Protein

Sujet: PGAM1 belongs to the phosphoglycerate mutase family. This protein is important components of glucose and 2,3-BPGA (2,3-bisphosphoglycerate) metabolism and catalyzes the reversible reaction of 3-phosphoglycerate (3-PGA) to 2-phosphoglycerate (2-PGA) in the glycolytic pathway. The PGAM is a dimeric enzyme containing, in different tissues, different proportions of a slow-migrating muscle (MM) isozyme, a fast-migrating brain (BB) isozyme, and a hybrid form (MB). Mutations in this protein cause muscle phosphoglycerate mutase eficiency, also known as glycogen storage disease X. Recombinant human PGAM protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: Phosphoglycerate mutase isozyme B, PGAM-B, PGAMA, Phosphoglycerate mutase 1. NCBI no.: NP_002620

Poids moléculaire: 30.9 kDa (274aa), confirmed by MALDI-TOF

Pathways: Regulation of Carbohydrate Metabolic Process