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QPRT Protein (AA 1-297) (His tag)

QPRT Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant > 95 % by SDS - PAGE SDS
N° du produit ABIN667206
  • Antigène Voir toutes QPRT Protéines
    QPRT (Quinolinate Phosphoribosyltransferase (QPRT))
    Type de proteíne
    Recombinant
    Attributs du protein
    AA 1-297
    Origine
    • 6
    • 1
    • 1
    • 1
    • 1
    Humain
    Source
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification/Conjugué
    Cette QPRT protéine est marqué à la His tag.
    Application
    SDS-PAGE (SDS)
    Attributs du produit
    QPRT, 1-297aa, Human, His tag, E.coli
    Pureté
    > 95 % by SDS - PAGE
    Top Product
    Discover our top product QPRT Protéine
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1mg/ml (determined by Bradford assay)
    Buffer
    Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 10% glycerol
    Stock
    4 °C
  • Antigène
    QPRT (Quinolinate Phosphoribosyltransferase (QPRT))
    Autre désignation
    QPRT (QPRT Produits)
    Synonymes
    ECK0108 Protein, JW0105 Protein, VF2184 Protein, QPRTase Protein, 2410027J01Rik Protein, AI647766 Protein, quinolinate phosphoribosyltransferase Protein, nicotinate-nucleotide pyrophosphorylase Protein, nicotinate-nucleotide diphosphorylase Protein, carboxylating Protein, ECs0113 Protein, nadC Protein, VP2522 Protein, STY0167 Protein, BJE04_RS13210 Protein, QPRT Protein, Qprt Protein
    Sujet
    Quinolinate phosphoribosyltransferase, also known as QPRT, is a major enzyme in the catabolism of quinolinate. It is an intermediate in the tryptophannicotinamide adenine dinucleotide (NAD) pathway, leading to the production of nicotinic acid, carbon dioxide and pyrophosphate. Elevation of QPRT levels in the brain has been linked to the pathogenesis of neurodegenerative disorders such as epilepsy, Alzheimer's disease, and Huntington's disease. Recombinant human QPRT protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: Nicotinate nucleotide pyrophosphorylase carboxylating, Quinolinate phosphoribosyltransferase , QPRTase, QAPRTase. NCBI no.: NP_055113
    Poids moléculaire
    32.9 kDa (317aa), confirmed by MALDI-TOF
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