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SH2D1A Protein (AA 1-128) (His tag)

SH2D1A Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant > 95 % by SDS - PAGE SDS
N° du produit ABIN667264
  • Antigène Voir toutes SH2D1A Protéines
    SH2D1A (SH2 Domain Containing 1A (SH2D1A))
    Type de proteíne
    Recombinant
    Attributs du protein
    AA 1-128
    Origine
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    Humain
    Source
    • 5
    • 4
    • 1
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification/Conjugué
    Cette SH2D1A protéine est marqué à la His tag.
    Application
    SDS-PAGE (SDS)
    Attributs du produit
    SH2D1A, 1-128aa, Human, His tag, E.coli
    Pureté
    > 95 % by SDS - PAGE
    Top Product
    Discover our top product SH2D1A Protéine
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1mg/ml (determined by Bradford assay)
    Buffer
    Liquid. In 20 mM Tris-HCl Buffer (pH 7.5) containing 1 mM DTT, 10% Glycerol
    Stock
    4 °C
  • Antigène
    SH2D1A (SH2 Domain Containing 1A (SH2D1A))
    Autre désignation
    SH2D1A (SH2D1A Produits)
    Synonymes
    DSHP Protein, EBVS Protein, IMD5 Protein, LYP Protein, MTCP1 Protein, SAP Protein, SAP/SH2D1A Protein, XLP Protein, XLPD Protein, RGD1562408 Protein, Gm686 Protein, SH2D1A Protein, SH2 domain containing 1A Protein, SH2D1A Protein, Sh2d1a Protein
    Sujet
    SH2D1A is an inhibitor of the signaling lymphocyte activation molecule (SLAM) self-association. This protein is expressed at a high level in thymus and lung, with a lower level of expression in spleen and liver. Defects in SH2D1A are a cause of X-linked lymphoproliferative disease (XLPD) also known as Duncan disease. XLPD is characterized by a rare congenital immunodeficiency following Epstein-Barr virus (EBV) infection. Recombinant human SH2D1A protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. Synonyms: SH2 domain-containing protein 1A, DSHP, EBVS, IMD5, LYP, MTCP1, SAP, XLP, XLPD. NCBI no.: NP_002342
    Poids moléculaire
    16.3 kDa(148aa), confirmed by MALDI-TOF
    Pathways
    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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