PNP Protein (AA 1-289) (His tag)
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- Antigène Voir toutes PNP (NP) Protéines
- PNP (NP) (Nucleoside Phosphorylase (NP))
- Type de proteíne
- Recombinant
- Attributs du protein
- AA 1-289
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Origine
- Humain
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Source
- Escherichia coli (E. coli)
- Purification/Conjugué
- Cette PNP protéine est marqué à la His tag.
- Application
- SDS-PAGE (SDS)
- Attributs du produit
- PNP, 1-289aa, Human, His tag, E.coli
- Pureté
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product NP Protéine
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/ml (determined by Bradford assay)
- Buffer
- Liquid. In 20 mM Tris-HCl buffer (pH8.0) containing 0.1M NaCl, 2mM DTT, 10% glycerol
- Stock
- 4 °C
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- Antigène
- PNP (NP) (Nucleoside Phosphorylase (NP))
- Autre désignation
- PNP (NP Produits)
- Synonymes
- NP Protein, PRO1837 Protein, PUNP Protein, Np Protein, AL024301 Protein, AU015798 Protein, Np-1 Protein, Np-2 Protein, Pnp1 Protein, purine nucleoside phosphorylase Protein, purine-nucleoside phosphorylase Protein, PNP Protein, Pnp Protein
- Classe de substances
- Viral Protein
- Sujet
- PNP belongs to the PNP/MTAP phosphorylase family of proteins. This protein catalyzes the reversible phosphorolysis of ribonucleosides and 2’-deoxyribonucleosides with specificity for guanine, hypoxanthine and their analogs. PNP deficiency is a rare autosomal recessive genetic disease associated with a severe defect in T-lymphocyte function and neurologic disorder in children, comprising four percent of combined immunodeficiency cases. Recombinant human PNP protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: Purine nucleoside phosphorylase, NP, Inosine phosphorylase, PRO1837, PUNP. NCBI no.: NP_000261
- Poids moléculaire
- 34.2 kDa (309aa) confirmed by MALDI-TOF
- Pathways
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Ribonucleoside Biosynthetic Process, Positive Regulation of Response to DNA Damage Stimulus
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