PTGDS Protein (AA 23-190) (His tag)

N° du produit ABIN667417

Détail du produit

Antigène: PTGDS (Prostaglandin D2 Synthase (PTGDS))

Type de proteíne: Recombinant

Attributs du protein: AA 23-190

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette PTGDS protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Attributs du produit: PTGDS, 23-190aa, Human, His tag, E.coli

Pureté: > 90 % by SDS - PAGE

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/ml (determined by BCA assay)

Buffer: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 30% glycerol, 1mM EDTA, 0.1M NaCl

Stock: 4 °C

Détail du antigène

Antigène: PTGDS (Prostaglandin D2 Synthase (PTGDS))

Autre désignation: PTGDS (PTGDS Produits)

Synonymes: 6PGD Protein, GSTS Protein, GSTS1-1 Protein, PGD2 Protein, PGDS Protein, L-PGDS Protein, LPGDS Protein, PDS Protein, PGDS2 Protein, H-PGDS Protein, Ptgds2 Protein, 21kDa Protein, Ptgs3 Protein, PH2DISO Protein, phosphogluconate dehydrogenase Protein, hematopoietic prostaglandin D synthase Protein, prostaglandin D2 synthase Protein, prostaglandin D2 synthase (brain) Protein, prostaglandin D synthase Protein, prostaglandin D2 synthase 21kDa (brain) Protein, PGD Protein, HPGDS Protein, PTGDS Protein, Hpgds Protein, Ptgds Protein, LOC100009453 Protein

Sujet: Prostaglandin-H2 D-isomerase, also known as PTGDS, is a glutathione-independent prostaglandin D synthase that catalyzes the conversion of prostaglandin H2 (PGH2) to postaglandin D2 (PGD2). It is likely to play important roles in both maturation and maintenance of the central nervous system and male reproductive system. PTGDS is the most abundant protein in the cerebral spinal fluid and recent evidence suggests that PTGDS acts as a beta-amyloid chaperone and may have a role in the deposition of Ab plaques in Alzheimer’s disease. Recombinant human PTGDS protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: Prostaglandin-H2 D-isomerase, L-PGDS, LPGDS, PDS, PGD2, PGDS, PGDS2. NCBI no.: NP_000945

Poids moléculaire: 20.9 kDa (189aa), confirmed by MALDI-TOF