CIRP Protein, Cirp Protein, R74941 Protein, Xcirp Protein, cirbp Protein, cirbp-a Protein, cirbp2 Protein, cirp Protein, cirp1 Protein, cirp2 Protein, xcirp2 Protein, XCIRP Protein, XCIRP-1 Protein, cirbp-b Protein, cirp-1 Protein, APBP-1 Protein, zgc:136559 Protein, CIRBP Protein, A18 hnRNP Protein, cold inducible RNA binding protein Protein, cold-inducible RNA-binding protein Protein, cold inducible RNA binding protein S homeolog Protein, cold inducible RNA binding protein L homeolog Protein, cold inducible RNA binding protein b Protein, CIRBP Protein, EDI_107320 Protein, Cirbp Protein, cirbp.S Protein, cirbp.L Protein, cirbp Protein, cirbpb Protein
Sujet
Cold inducible RNA-binding protein, also known as CIRBP, plays a protective role in the genotoxic stress response by stabilizing transcripts of genes involved in cell survival. It is localizes to the nucleus and contains one RRM (RNA recognition motif) domain. Expressed ubiquitously, CIRBP is thought to play an essential role in the suppression of cellular proliferation in response to UV irradiation or extreme cold. Recombinant human CIRBP protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: Cold inducible RNA-binding protein, CIRP, A18HNRNP. NCBI no.: NP_001271