SNIP1 Protein (AA 258-396) (His tag)

N° du produit ABIN667459

Détail du produit

Antigène: SNIP1 (Smad Nuclear Interacting Protein 1 (SNIP1))

Type de proteíne: Recombinant

Attributs du protein: AA 258-396

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette SNIP1 protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Attributs du produit: SNIP1, 258-396aa, Human, His tag, E.coli

Pureté: > 90 % by SDS - PAGE

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1mg/ml (determined by Bradford assay)

Buffer: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 2mM DTT, 20% glycerol, 100mM NaCl

Stock: 4 °C

Détail du antigène

Antigène: SNIP1 (Smad Nuclear Interacting Protein 1 (SNIP1))

Autre désignation: SNIP1 (SNIP1 Produits)

Synonymes: MGC75890 Protein, snip1a Protein, SNIP1 Protein, PMRED Protein, 2410133M08Rik Protein, Smad nuclear interacting protein 1 Protein, Smad nuclear interacting protein 1 S homeolog Protein, smad nuclear interacting protein 1 Protein, MYST/Esa1 associated factor 6 Protein, snip1 Protein, snip1.S Protein, SNIP1 Protein, CC1G_02914 Protein, PTRG_06240 Protein, MEAF6 Protein, Snip1 Protein

Sujet: SNIP1 is smad nuclear interacting protein contains a forkhead-associated (FHA) domain and acts as a nuclear inhibitor of CBP/p300. This protein is an inhibitor of the TGF-beta signal transduction pathway and to be important in suppressing transcriptional activation dependent on the co-activators CBP and p300. Inhibition of NF-kappa B activity is a function of the N-terminal domain of SNIP1 and involves competition of SNIP1 and the NF-kappa B subunit, RelA/p65, for binding to p300, similar to the mechanism of inhibition of Smad signaling by SNIP1. Recombinant human SNIP1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: Smad nuclear interacting protein 1, FLJ12553, Splicing factor arginine/serine rich 4. NCBI no.: NP_078976

Poids moléculaire: 18.8kDa (160aa), confirmed by MALDI-TOF

Pathways: SARS-CoV-2 Protein Interactome, Phosphorylation & l'infection par le SRAS-CoV-2