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Oncostatin M Protein (OSM) (AA 26-234) (His tag)

OSM Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant > 95 % by SDS - PAGE SDS
N° du produit ABIN667495
  • Antigène Voir toutes Oncostatin M (OSM) Protéines
    Oncostatin M (OSM)
    Type de proteíne
    Recombinant
    Attributs du protein
    AA 26-234
    Origine
    • 25
    • 7
    • 4
    • 3
    • 1
    • 1
    Humain
    Source
    • 21
    • 13
    • 1
    • 1
    • 1
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification/Conjugué
    Cette Oncostatin M protéine est marqué à la His tag.
    Application
    SDS-PAGE (SDS)
    Attributs du produit
    OSM, 26-234aa, Human, His tag, E.coli
    Pureté
    > 95 % by SDS - PAGE
    Top Product
    Discover our top product OSM Protéine
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.5 mg/ml (determined by Bradford assay)
    Buffer
    Liquid. 20mM Tris-HCl buffer (pH8.0) containing 20% glycerol, 1mM DTT
    Stock
    4 °C
  • Antigène
    Oncostatin M (OSM)
    Autre désignation
    OSM (OSM Produits)
    Synonymes
    OSM Protein, OncoM Protein, oncostatin M Protein, OSM Protein, Osm Protein
    Sujet
    OSM, also known as Oncostatin M, is a pleiotropic cytokine that belongs to the interleukin 6 group of cytokines. Of these cytokines it most closely resembles leukemia inhibitory factor (LIF) in both structure and function. However, it is as yet poorly defined and is proving important in liver development, haematopoeisis, inflammation and possibly CNS development. It is also associated with bone formation and destruction. OSM signals through cell surface receptors that contain the protein gp130. The type I receptor is composed of gp130 and LIFR, the type II receptor is composed of gp130 and OSMR. Recombinant human OSM protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. Synonyms: Oncostatin M, MGC20461, Oncostatin M precursor. NCBI no.: NP_065391
    Poids moléculaire
    25.9 kDa (230aa), confirmed by MALDI-TOF
    Pathways
    Signalistation JAK/STAT, Negative Regulation of Hormone Secretion
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