SHC1 Protein (AA 1-474) (His tag)
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- Antigène Voir toutes SHC1 Protéines
- SHC1 (SHC (Src Homology 2 Domain Containing) Transforming Protein 1 (SHC1))
- Type de proteíne
- Recombinant
- Attributs du protein
- AA 1-474
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Origine
- Humain
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Source
- Escherichia coli (E. coli)
- Purification/Conjugué
- Cette SHC1 protéine est marqué à la His tag.
- Application
- SDS-PAGE (SDS)
- Attributs du produit
- SHC1, 1-474aa, Human, His tag, E.coli
- Pureté
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product SHC1 Protéine
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1mg/ml (determined by Bradford assay)
- Buffer
- Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 2mM DTT, 20% glycerol, 200mM NaCl, 0.1mM PMSF
- Stock
- 4 °C
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- Antigène
- SHC1 (SHC (Src Homology 2 Domain Containing) Transforming Protein 1 (SHC1))
- Autre désignation
- SHC1 (SHC1 Produits)
- Synonymes
- SHC1 Protein, SHC Protein, SHCA Protein, P66shc Protein, si:dkey-246i14.4 Protein, wu:fc10h03 Protein, shc Protein, p66shc Protein, Shc Protein, ShcA Protein, p66 Protein, SHC adaptor protein 1 Protein, Shc1p Protein, squalene--hopene cyclase Protein, SHC (Src homology 2 domain containing) transforming protein 1 Protein, SHC (Src homology 2 domain containing) transforming protein 1 L homeolog Protein, src homology 2 domain-containing transforming protein C1 Protein, SHC1 Protein, shc1 Protein, Shc1 Protein, shc1.L Protein
- Sujet
- SHC1 (SHC-transforming protein 1) belongs to the SH2 domain family. SHC1 has been found to be important in the regulation of apoptosis and drug resistance in mammalian cells. It is a signaling adapter that couples activated growth factor receptors to signaling pathway. SHC1 expressed in neural stem cells but absent in mature neurons. Recombinant human SHC1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: SHC-transforming protein 1, FLJ26504, SH2 domain protein C1, SHC, SHC-transforming protein 3, p66, MGC98812, SHCA, Src homology 2 domain containing transforming protein C1. NCBI no.: NP_003020
- Poids moléculaire
- 53.8kDa (494aa)
- Pathways
- Signalisation RTK, TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, ER-Nucleus Signaling, Signaling Events mediated by VEGFR1 and VEGFR2
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