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PPME1 Protein (AA 1-386) (His tag)

PPME1 Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant > 95 % by SDS - PAGE SDS
N° du produit ABIN667510
  • Antigène Voir toutes PPME1 Protéines
    PPME1 (Protein Phosphatase Methylesterase 1 (PPME1))
    Type de proteíne
    Recombinant
    Attributs du protein
    AA 1-386
    Origine
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Source
    • 9
    • 2
    • 1
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification/Conjugué
    Cette PPME1 protéine est marqué à la His tag.
    Application
    SDS-PAGE (SDS)
    Attributs du produit
    PPME1, 1-386aa, Human, His tag, E.coli
    Pureté
    > 95 % by SDS - PAGE
    Top Product
    Discover our top product PPME1 Protéine
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.5 mg/ml (determined by Bradford assay)
    Buffer
    Liquid. 20mM Tris-HCl buffer (pH8.0) containing 20% glycerol, 0.1M NaCl,1mM DTT
    Stock
    4 °C
  • Antigène
    PPME1 (Protein Phosphatase Methylesterase 1 (PPME1))
    Autre désignation
    PPME1 (PPME1 Produits)
    Synonymes
    PME-1 Protein, 1110069N17Rik Protein, 2700017M01Rik Protein, Pme1 Protein, fk72d03 Protein, zgc:56239 Protein, wu:fk72d03 Protein, RGD1309683 Protein, PME1MGC133824 Protein, F28M11.4 Protein, DDBDRAFT_0204584 Protein, DDBDRAFT_0305014 Protein, DDB_0204584 Protein, DDB_0305014 Protein, PME1 Protein, CaO19.1459 Protein, protein phosphatase methylesterase 1 Protein, protein phosphatase methylesterase 1 S homeolog Protein, esterase/lipase/thioesterase family protein Protein, carboxylesterase-mitochondrial 37S ribosomal protein YmS2 Protein, PPME1 Protein, Ppme1 Protein, ppme1 Protein, ppme1.S Protein, AT4G10050 Protein, PPE1 Protein
    Sujet
    PPME1, also known protein phosphatase methylesterase-1(PME1), catalyzes the demethylation and inactivation of protein phosphatase (PP2A), which is a multimeric phosphoserine/ threonine protein phosphatase associated with growth inhibition and cell cycle arrest. It can demethylate PP2A catalytic subunit in vitro and okadaic acid treatment is capable of inhibiting this reaction. It is conserved from yeast to human and contains a motif found in lipases having a catalytic triad activated serine as their active site nucleophile. Recombinant human PPME1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. Synonyms: Protein phosphatase methylesterase 1, FLJ22226, PME-1. NCBI no.: NP_057231
    Poids moléculaire
    44.4 kDa(406aa), confirmed by MALDI-TOF
    Pathways
    Methionine Biosynthetic Process
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