CLCF1 Protein (AA 28-225) (His tag)
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- Antigène Voir toutes CLCF1 Protéines
- CLCF1 (Cardiotrophin-Like Cytokine Factor 1 (CLCF1))
- Type de proteíne
- Recombinant
- Attributs du protein
- AA 28-225
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Origine
- Humain
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Source
- Escherichia coli (E. coli)
- Purification/Conjugué
- Cette CLCF1 protéine est marqué à la His tag.
- Application
- SDS-PAGE (SDS)
- Attributs du produit
- CLCF1, 28-225aa, Human, His tag, E.coli
- Pureté
- > 90 % by SDS - PAGE
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/ml (determined by Bradford assay)
- Buffer
- Liquid. 20mM sodium citrate (pH 3.5), 0.4M Urea, 10% glycerol
- Stock
- 4 °C
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- Antigène
- CLCF1 (Cardiotrophin-Like Cytokine Factor 1 (CLCF1))
- Autre désignation
- CLCF1 (CLCF1 Produits)
- Sujet
- CLCF1, also known as cardiotrophin-like cytokine factor 1, belongs to the interleukin 6 family of cytokines, which are involved in cell signaling through phosphorylation of gp130. CLCF1 has a sequence of 225-amino acids with a 27-aa signal peptide, a molecular mass of 22 kDa in mature form, and the highest homology to cardiotrophin-1 and ciliary neurotrophic factor. CLCF1 can be actively secreted from cells by forming a complex with soluble type I CRLF1 or soluble CNTFR. Defects in CLCF1 cause cold-induced sweating syndrome 2 (CISS2). This syndrome is characterized by a profuse sweating after exposure to cold as well as congenital physical abnormalities of the head and spine. Synonyms: Cardiotrophin-like cytokine factor 1, BSF-3, BSF3, CISS2, CLC, NNT-1, NNT1, NR6. NCBI no.: NP_037378
- Poids moléculaire
- 24.6 kDa (219aa)
- Pathways
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
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