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CDKN2C Protein (AA 1-168) (His tag)

CDKN2C Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant > 95 % by SDS - PAGE SDS
N° du produit ABIN667655
  • Antigène Voir toutes CDKN2C Protéines
    CDKN2C (Cyclin-Dependent Kinase Inhibitor 2C (p18, Inhibits CDK4) (CDKN2C))
    Type de proteíne
    Recombinant
    Attributs du protein
    AA 1-168
    Origine
    • 7
    • 1
    Humain
    Source
    • 5
    • 2
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification/Conjugué
    Cette CDKN2C protéine est marqué à la His tag.
    Application
    SDS-PAGE (SDS)
    Attributs du produit
    CDKN2C, 1-168aa, Human, His tag, E.coli
    Pureté
    > 95 % by SDS - PAGE
    Top Product
    Discover our top product CDKN2C Protéine
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.5mg/ml (determined by Bradford assay)
    Buffer
    Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 2mM DTT, 10% glycerol, 200mM NaCl
    Stock
    4 °C
  • Antigène
    CDKN2C (Cyclin-Dependent Kinase Inhibitor 2C (p18, Inhibits CDK4) (CDKN2C))
    Autre désignation
    CDKN2C (CDKN2C Produits)
    Synonymes
    CDKN2C Protein, p18 Protein, ink4c Protein, p18-ink4c Protein, INK4C Protein, p18-INK4C Protein, C77269 Protein, INK4c Protein, INK4d Protein, p18INK4c Protein, cyclin dependent kinase inhibitor 2C Protein, cyclin-dependent kinase inhibitor 2C Protein, cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) Protein, CDKN2C Protein, cdkn2c Protein, Cdkn2c Protein
    Sujet
    CDKN2C (Cyclin-dependent kinase 4 inhibitor C ) belongs to the CDKN2 cyclin-dependent kinase inhibitor family. It has been shown to interact with CDK4 or CDK6, and prevent the activation of the CDK kinases, thus function as a cell growth regulator that controls cell cycle G1 progression. And this protein suppresses the cell growth and proliferation with a correlated dependence on endogenous retinoblastoma protein RB. Studies in the knockout mice suggested the roles of this gene in regulating spermatogenesis, as well as in suppressing tumorigenesis. Recombinant human CDKN2C protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: Cyclin-dependent kinase 4 inhibitor C, INK4C, p18, p18-INK4C. NCBI no.: NP_001253
    Poids moléculaire
    20.7kDa (192aa), confirmed by MALDI-TOF
    Pathways
    Cycle Cellulaire, Mitotic G1-G1/S Phases
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