CPI-17 Protein (AA 1-147) (His tag)

N° du produit ABIN667711

Détail du produit

Antigène: CPI-17 (PPP1R14A) (Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 14A (PPP1R14A))

Type de proteíne: Recombinant

Attributs du protein: AA 1-147

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette CPI-17 protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Attributs du produit: PPP1R14A , 1-147aa, Human, His-tagged, Recombinant, E.coli

Pureté: > 95 % by SDS - PAGE

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/ml (determined by Bradford assay)

Buffer: Liquid in 20mM Tris pH 8.0, 2mM EDTA, 1mM DTT, 10% glycerol

Stock: 4 °C

Détail du antigène

Antigène: CPI-17 (PPP1R14A) (Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 14A (PPP1R14A))

Autre désignation: PPP1R14A (PPP1R14A Produits)

Synonymes: MGC81874 Protein, cpi-17 Protein, ppp1inl Protein, CPI-17 Protein, im:7147597 Protein, ppp1r14a Protein, zgc:110700 Protein, PPP1R14A Protein, CPI17 Protein, PPP1INL Protein, Cpi17 Protein, 1110001M11Rik Protein, protein phosphatase 1 regulatory inhibitor subunit 14A L homeolog Protein, protein phosphatase 1 regulatory inhibitor subunit 14A Protein, protein phosphatase 1, regulatory (inhibitor) subunit 14Aa Protein, protein phosphatase 1, regulatory (inhibitor) subunit 14A Protein, ppp1r14a.L Protein, ppp1r14a Protein, ppp1r14aa Protein, PPP1R14A Protein, Ppp1r14a Protein

Sujet: PPP1R14A (Protein phosphatase 1 regulatory subunit 14A) is a phosphorylation-dependent inhibitory protein for smooth muscle myosin phosphate. Myosin phosphatase can reverse MYL (myosin light chain) phosphorylation to induce a state of relaxation. However, during agonist-induced contraction at constant Ca2+ concurrent inhibition of myosin phosphatase leads to increases in MYL phosphorylation and tension. These calcium-independent increases in myosin phosphorylation and tension are termed calcium sensitization. Recombinant His tagged PPP1R14A was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: CPI17, CPI-17, PPP1INL, Protein phosphatase 1, regulatory (inhibitor) subunit 14A, PPP1R14A , Protein phosphatase 1, regulatory (inhibitor) subunit 14A CPI 17, CPI 17 alpha, CPI 17alpha, CPI17, PKC potentiated inhibitory protein of PP1, Protein phosphatase 1 regulatory (inhibitor) subunit 14A, Protein phosphatase 1 regulatory subunit 14A, Regulatory subunit 14A,. NCBI no.: NP_150281

Poids moléculaire: 18 kDa (167 aa), confirmed by MALDI-TOF.