Calreticulin Protein (CALR) (AA 18-417) (His tag)

N° du produit ABIN667783

Détail du produit

Antigène: Calreticulin (CALR)

Type de proteíne: Recombinant

Attributs du protein: AA 18-417

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette Calreticulin protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Attributs du produit: Calreticulin, 18-417aa, Human, His tag, E.coli

Pureté: > 85 % by SDS - PAGE

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/ml (determined by Bradford assay)

Buffer: Liquid. In 20 mM Tris-HCl buffer (pH8.0) containing 1mM DTT, 0.1M Nacl, 10% glycerol

Stock: 4 °C

Détail du antigène

Antigène: Calreticulin (CALR)

Autre désignation: Calreticulin (CALR Produits)

Sujet: Calreticulin is the major calcium binding protein found in smooth muscle sarcoplasmic reticulum (SR) and non-muscle endoplasmic reticulum (ER) membranes. Calreticulin can inhibit the binding of androgen receptor to its hormone-responsive DNA element and can inhibit androgen receptor and retinoic acid receptor transcriptional activities in vivo, as well as retinoic acid-induced neuronal differentiation. Thus, Calreticulin can act as an important modulator of the regulation of gene transcription by nuclear hormone receptors. Recombinant human Calreticulin protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: cC1qR, CRT, FLJ26680, RO, SSA, Autoantigen RO, CALR, CALR protein, Calregulin, Calreticulin, CRP55, CRTC, ERp60, FLJ26680, grp60, HACBP, Sicca syndrome antigen A. NCBI no.: NP_004334

Poids moléculaire: 48.7 kDa (421aa), confirmed by MALDI-TOF

Pathways: Retinoic Acid Receptor Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Nuclear Hormone Receptor Binding, ER-Nucleus Signaling, Unfolded Protein Response