TOLLIP Protein (AA 1-274) (His tag)
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- Antigène Voir toutes TOLLIP Protéines
- TOLLIP (Toll Interacting Protein (TOLLIP))
- Type de proteíne
- Recombinant
- Attributs du protein
- AA 1-274
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Origine
- Humain
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Source
- Escherichia coli (E. coli)
- Purification/Conjugué
- Cette TOLLIP protéine est marqué à la His tag.
- Application
- SDS-PAGE (SDS)
- Attributs du produit
- TOLLIP, 1-274aa, Human, His tag, E.coli
- Pureté
- > 85 % by SDS - PAGE
- Top Product
- Discover our top product TOLLIP Protéine
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.25 mg/ml (determined by Bradford assay)
- Buffer
- Liquid. 20mM Tris-HCl buffer (pH8.0) containing 40% glycerol, 0.2M NaCl,2mM DTT
- Stock
- 4 °C
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- Antigène
- TOLLIP (Toll Interacting Protein (TOLLIP))
- Autre désignation
- TOLLIP (TOLLIP Produits)
- Synonymes
- IL-1RAcPIP Protein, 4930403G24Rik Protein, 4931428G15Rik Protein, fk22a02 Protein, im:7145391 Protein, wu:fk22a02 Protein, zgc:76985 Protein, TOLLIP Protein, GB17961 Protein, tollip Protein, tollip1 Protein, tollipa Protein, TOLIP Protein, toll interacting protein Protein, toll-interacting protein Protein, toll-interacting protein-like Protein, toll interacting protein L homeolog Protein, toll interacting protein S homeolog Protein, Toll-interleukine I receptor interacting protein I Protein, TOLLIP Protein, Tollip Protein, tollip Protein, LOC552034 Protein, LOC100169858 Protein, tollip.L Protein, tollip.S Protein, LOC100136122 Protein
- Sujet
- TOLLIP, also known as Toll interacting protein, is an inhibitory adaptor protein within Toll-like receptors. The TLR pathway is a part of the innate immune system that recognizes structurally conserved molecular patterns of microbial pathogens, leading to an inflammatory immune response. Negative regulation of TLR signaling by TOLLIP may limit the production of proinflammatory mediators during inflammation and infection. Also, it forms a complex with Tom1 to regulate endosomal trafficking of ubiquitinated proteins. Recombinant human TOLLIP protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. Synonyms: Toll interacting protein, FLJ33531, IL-1RAcPIP. NCBI no.: NP_061882
- Poids moléculaire
- 32.4 kDa (294aa) confirmed by MALDI-TOF
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