PCK1 Protein (AA 1-622) (His tag)

N° du produit ABIN668008

Détail du produit

Antigène: PCK1 (phosphoenolpyruvate Carboxykinase 1 (Soluble) (PCK1))

Type de proteíne: Recombinant

Attributs du protein: AA 1-622

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette PCK1 protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Attributs du produit: PCK1, 1-622aa, Human, His tag, E.coli

Pureté: > 90 % by SDS - PAGE

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/ml (determined by Bradford assay)

Buffer: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 10% glycerol, 0.1M NaCl

Stock: 4 °C

Détail du antigène

Antigène: PCK1 (phosphoenolpyruvate Carboxykinase 1 (Soluble) (PCK1))

Autre désignation: PCK1 (PCK1 Produits)

Synonymes: PEPCK-C Protein, PEPCK1 Protein, PEPCKC Protein, PEPCK Protein, PEPCK-M Protein, PEPCK2 Protein, 1810010O14Rik Protein, 9130022B02Rik Protein, cb856 Protein, cb924 Protein, fj93h11 Protein, zgc:63869 Protein, wu:fc51c05 Protein, wu:fj93h11 Protein, pepck-c Protein, pepck1 Protein, pepckc Protein, PCK1 Protein, PPCK1 Protein, AI265463 Protein, Pck-1 Protein, GTP Protein, PCK Protein, Pepck Protein, RATPEPCK Protein, Ppc1C Protein, PHOSPHOENOLPYRUVATE CARBOXYKINASE Protein, T28I19.150 Protein, T28I19_150 Protein, phosphoenolpyruvate carboxykinase 1 Protein, 143299_at Protein, CG10924 Protein, CG17725 Protein, Dmel\\CG17725 Protein, Dromel_CG17725_FBtr0086701_pepck_mORF Protein, dPEPCK Protein, pepck Protein, PEPC Protein, PEPCase Protein, ppc Protein, phosphoenolpyruvate carboxykinase 1 Protein, phosphoenolpyruvate carboxykinase 2, mitochondrial Protein, phosphoenolpyruvate carboxykinase 2 (mitochondrial) Protein, phosphoenolpyruvate carboxykinase 1 (soluble) Protein, phosphoenolpyruvate carboxykinase 1 S homeolog Protein, phosphoenolpyruvate carboxykinase, cytosolic [GTP] Protein, phosphoenolpyruvate carboxykinase 1, cytosolic Protein, phosphoenolpyruvate carboxylase 7 Protein, Phosphoenolpyruvate carboxykinase Protein, phosphoenolpyruvate carboxylase Protein, PCK1 Protein, PCK2 Protein, Pck2 Protein, pck1 Protein, pck1.S Protein, LOC100634531 Protein, Pck1 Protein, pep7 Protein, Pepck Protein, LOC107777405 Protein

Sujet: Phosphoenolpyruvate carboxykinase 1, also known as PCK1, is a main control point for the regulation of gluconeogenesis. PCK1 plays an important role in this process by stimulating hepatic glucose production. The expression of PCK1 can be regulated by insulin, glucocorticoids, glucagon, cAMP, and diet. Modulation of the signals governing PCK1 levels presents a potential therapeutic approach to the treatment of Insulin resistance and consequently obesity. Recombinant human PCK1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: Phosphoenolpyruvate carboxykinase 1, PEPCK-C, PEPCK1, PEPCKC. NCBI no.: AAH23978

Poids moléculaire: 71.7 kDa (646aa)

Pathways: Positive Regulation of Peptide Hormone Secretion, Carbohydrate Homeostasis