TIFA Protein (AA 1-184) (His tag)
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- Antigène Voir toutes TIFA Protéines
- TIFA (TRAF-Interacting Protein with Forkhead-Associated Domain (TIFA))
- Type de proteíne
- Recombinant
- Attributs du protein
- AA 1-184
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Origine
- Humain
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Source
- Escherichia coli (E. coli)
- Purification/Conjugué
- Cette TIFA protéine est marqué à la His tag.
- Application
- SDS-PAGE (SDS)
- Attributs du produit
- TIFA, 1-184aa , Human, His tag, E.coli
- Pureté
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product TIFA Protéine
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/ml (determined by Bradford assay)
- Buffer
- Liquid. 20mM Tris-HCl buffer (pH8.0) containing 20% glycerol, 1mM DTT
- Stock
- 4 °C
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- Antigène
- TIFA (TRAF-Interacting Protein with Forkhead-Associated Domain (TIFA))
- Autre désignation
- TIFA (TIFA Produits)
- Synonymes
- TIFA Protein, xtifa Protein, T2BP Protein, T6BP Protein, TIFAA Protein, T2bp Protein, Ab2-389 Protein, TRAF interacting protein with forkhead associated domain Protein, TRAF-interacting protein with forkhead-associated domain Protein, TRAF-interacting protein with forkhead-associated domain S homeolog Protein, TIFA Protein, tifa Protein, Tifa Protein, tifa.S Protein
- Sujet
- TIFA, also known as TRAF-interacting protein with FHA domain-containing protein A, is an adapter protein which mediates the IRAK1 and TRAF6 interaction following IL-1 stimulation, resulting in the downstream activation of NF-kappa-B and AP-1 pathways. This protein induces the oligomerization and polyubiquitination of TRAF6, which leads to the activation of TAK1 and IKK through a proteasome-independent mechanism. Recombinant human TIFA protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. Synonyms: TRAF-interacting protein with FHA domain-containing protein A, T2BP, T6BP, TIFAA. NCBI no.: NP_443096
- Poids moléculaire
- 24.0 kDa (208aa) confirmed by MALDI-TOF
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