NQO1 Protein (AA 1-274) (His tag)

N° du produit ABIN668043

Détail du produit

Antigène: NQO1 (NAD(P)H Dehydrogenase, Quinone 1 (NQO1))

Type de proteíne: Recombinant

Attributs du protein: AA 1-274

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette NQO1 protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Attributs du produit: NQO1, 1-274 aa, Human, His-tagged, Recombinant, E.coli

Pureté: > 95 % by SDS-PAGE

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/ml (determined by Bradford assay)

Buffer: Liquid. In 20mM Tris-HCL buffer (pH 8.0) containing 10% glycerol 1mM DTT.

Stock: 4 °C

Détail du antigène

Antigène: NQO1 (NAD(P)H Dehydrogenase, Quinone 1 (NQO1))

Autre désignation: NQO1 (NQO1 Produits)

Synonymes: zgc:77191 Protein, wu:fb63c10 Protein, nqo1 Protein, DHQU Protein, DIA4 Protein, DTD Protein, NMOR1 Protein, NMORI Protein, QR1 Protein, Dia4 Protein, AV001255 Protein, Dtd Protein, Nmo-1 Protein, Nmo1 Protein, Nmor1 Protein, Ox-1 Protein, Ox1 Protein, Qr1 Protein, NADPH-d Protein, NAD(P)H dehydrogenase, quinone 1 Protein, NAD(P)H quinone dehydrogenase 1 Protein, NAD(P)H dehydrogenase, quinone 1 L homeolog Protein, nqo1 Protein, NQO1 Protein, Bpet2092 Protein, nqo1.L Protein, Nqo1 Protein

Sujet: NQO1 is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. This protein apparently serves as a quinone reductase in connection with conjugation reactions of hydroquinons involved in detoxification pathways as well as in biosynthetic processes such as the vitamin K-dependent gamma-carboxylation of glutamate residues in prothrombin synthesis. NQO1 functions as an important part of cellular antioxidant defense by detoxifying quinines thus preventing the formation of reactive oxygen species. Altered expression of NQO1 has been seen in many tumors and is also associated with Alzheimer’s disease (AD). Recombinant NQO1 protein was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: DHQU, DIA4, DTD, NMOR1, NMORI, QR1, Azoreductase, Quinone reductase 1, DT-diaphorase, NAD(P)H dehydrogenase, quinone 1, Azoreductase.Menadione reductase, NQO 1, QR 1, Phylloquinone reductase, Cytochrome b 5 reductase, DIA 4, Diaphorase (NADH/NADPH), Diaphorase 4 Dioxin inducible 1, DT diaphorase, Diaphorase (NADH/NADPH) (cytochrome b 5 reductase), NAD(P)H dehydrogenase quinone 1 NAD(P)H menadione oxidoreductase 1 dioxin inducible, NAD(P)H: menadione oxidoreductase 1 dioxin inducible 1, NAD(P)H:menadione oxidoreductase 1, NAD(P)H:Quinone acceptor oxidoreductase type 1, NAD(P)H:quinone oxidoreductase 1, NAD(P)H:quinone oxireductase, NMOR 1, NMOR I. NCBI no.: NP_000894

Poids moléculaire: 33.0 kDa (294aa), confirmed by MALDI-TOF.