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HHLA2 Protein (AA 23-344) (Fc Tag)

HHLA2 Origine: Humain Hôte: HEK-293 Cells Recombinant >90 % as determined by reduced SDS-PAGE. Active
N° du produit ABIN6809928
  • Antigène Voir toutes HHLA2 Protéines
    HHLA2 (HERV-H LTR-Associating 2 (HHLA2))
    Type de proteíne
    Recombinant
    Activité biologique
    Active
    Attributs du protein
    AA 23-344
    Origine
    • 7
    • 2
    Humain
    Source
    • 7
    • 1
    • 1
    HEK-293 Cells
    Purification/Conjugué
    Cette HHLA2 protéine est marqué à la Fc Tag.
    Séquence
    AA 23-344
    Pureté
    >90 % as determined by reduced SDS-PAGE.
    niveau d'endotoxine
    Less than 1.0 EU per μg by the LAL method.
    Top Product
    Discover our top product HHLA2 Protéine
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    Tris with Glycine, Arginine and NaCl,  pH 7.5
    Conseil sur la manipulation
    Please avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
  • Antigène
    HHLA2 (HERV-H LTR-Associating 2 (HHLA2))
    Autre désignation
    B7-H7 (HHLA2 Produits)
    Synonymes
    B7H7 Protein, HERV-H LTR-associating 2 Protein, HHLA2 Protein, hhla2 Protein
    Sujet
    B7-H7 (HHLA2) is a newly identified B7 family member that regulates human T-cell functions. B7-H7 was previously known as human endogenous retrovirus-H long terminal repeat associating 2 (HHLA2) with unidentified function. Recently, B7-H7 has been identified as a specific ligand for human CD28H. The B7-H7-CD28H pathway strongly promoted CD4+ T-cell proliferation and cytokine production via an AKT-dependent signaling cascade in the presence of TCR signaling, suggesting B7-H7 comprises a new co-stimulatory pathway. The first IgV domain of B7-H7, which presumably binds to a putative receptor, shows the highest homology to other B7 family members.
    Poids moléculaire
    63.4 kDa
    NCBI Accession
    NP_009003
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