HHLA2 Protein (AA 23-344) (Fc Tag)
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- Antigène Voir toutes HHLA2 Protéines
- HHLA2 (HERV-H LTR-Associating 2 (HHLA2))
- Type de proteíne
- Recombinant
- Activité biologique
- Active
- Attributs du protein
- AA 23-344
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Origine
- Humain
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Source
- HEK-293 Cells
- Purification/Conjugué
- Cette HHLA2 protéine est marqué à la Fc Tag.
- Séquence
- AA 23-344
- Pureté
- >90 % as determined by reduced SDS-PAGE.
- niveau d'endotoxine
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product HHLA2 Protéine
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- Tris with Glycine, Arginine and NaCl, pH 7.5
- Conseil sur la manipulation
- Please avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
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- Antigène
- HHLA2 (HERV-H LTR-Associating 2 (HHLA2))
- Autre désignation
- B7-H7 (HHLA2 Produits)
- Synonymes
- B7H7 Protein, HERV-H LTR-associating 2 Protein, HHLA2 Protein, hhla2 Protein
- Sujet
- B7-H7 (HHLA2) is a newly identified B7 family member that regulates human T-cell functions. B7-H7 was previously known as human endogenous retrovirus-H long terminal repeat associating 2 (HHLA2) with unidentified function. Recently, B7-H7 has been identified as a specific ligand for human CD28H. The B7-H7-CD28H pathway strongly promoted CD4+ T-cell proliferation and cytokine production via an AKT-dependent signaling cascade in the presence of TCR signaling, suggesting B7-H7 comprises a new co-stimulatory pathway. The first IgV domain of B7-H7, which presumably binds to a putative receptor, shows the highest homology to other B7 family members.
- Poids moléculaire
- 63.4 kDa
- NCBI Accession
- NP_009003
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