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CD73 Protein (AA 27-549) (His tag)

NT5E Origine: Humain Hôte: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE.
N° du produit ABIN6809998
  • Antigène Voir toutes CD73 (NT5E) Protéines
    CD73 (NT5E) (5'-Nucleotidase, Ecto (CD73) (NT5E))
    Type de proteíne
    Recombinant
    Attributs du protein
    AA 27-549
    Origine
    • 15
    • 8
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    Humain
    Source
    • 16
    • 7
    • 5
    • 2
    • 1
    • 1
    • 1
    HEK-293 Cells
    Purification/Conjugué
    Cette CD73 protéine est marqué à la His tag.
    Séquence
    AA 27-549
    Pureté
    >90 % as determined by SDS-PAGE.
    niveau d'endotoxine
    Less than 1.0 EU per μg by the LAL method.
    Top Product
    Discover our top product NT5E Protéine
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    20 mM Tris, 120 mM NaCl, pH 7.5
    Conseil sur la manipulation
    Please avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
  • Antigène
    CD73 (NT5E) (5'-Nucleotidase, Ecto (CD73) (NT5E))
    Autre désignation
    CD73 (NT5E Produits)
    Synonymes
    CALJA Protein, CD73 Protein, E5NT Protein, NT Protein, NT5 Protein, NTE Protein, eN Protein, eNT Protein, zgc:63784 Protein, NT5E Protein, MGC114869 Protein, PSPTO2277 Protein, 2210401F01Rik Protein, AI447961 Protein, Nt5 Protein, 5'-nucleotidase ecto Protein, 5'-nucleotidase, ecto (CD73) Protein, 5'-nucleotidase Protein, 5' nucleotidase, ecto Protein, NT5E Protein, nt5e Protein, nt5e.S Protein, PSPTO_2277 Protein, CBU_1233 Protein, MCA1322 Protein, Nt5e Protein
    Sujet
    5'-nucleotidase (5'-NT), also known as ecto-5'-nucleotidase or CD73 (cluster of differentiation 73), is an enzyme that is encoded by the NT5E gene. CD73 commonly serves to convert AMP to adenosine. Ecto-5-prime-nucleotidase (5-prime-ribonucleotide phosphohydrolase) catalyzes the conversion at neutral pH of purine 5-prime mononucleotides to nucleosides, the preferred substrate being AMP. Other forms of 5-prime nucleotidase exist in the cytoplasm and lysosomes and can be distinguished from ecto-NT5 by their substrate affinities, requirement for divalent magnesium ion, activation by ATP, and inhibition by inorganic phosphate. Rare allelic variants are associated with a syndrome of adult-onset calcification of joints and arteries (CALJA) affecting the iliac, femoral, and tibial arteries reducing circulation in the legs and the joints of the hands and feet causing pain.
    Poids moléculaire
    59.9 kDa
    NCBI Accession
    NP_002517
    Pathways
    Synaptic Membrane, Ribonucleoside Biosynthetic Process
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