VHL Protein (AA 1-172) (GST tag)

N° du produit ABIN1325000

Détail du produit

Antigène: VHL (Von Hippel-Lindau Tumor Suppressor, E3 Ubiquitin Protein Ligase (VHL))

Type de proteíne: Recombinant

Attributs du protein: AA 1-172

Origine: Humain

Source: Wheat germ

Purification/Conjugué: Cette VHL protéine est marqué à la GST tag.

Application: Western Blotting (WB), ELISA, Antibody Array (AA), Affinity Purification (AP)

Fonction: VHL (Human) Recombinant Protein (P01)

Séquence: MPRRAENWDE AEVGAEEAGV EEYGPEEDGG EESGAEESGP EESGPEELGA EEEMEAGRPR PVLRSVNSRE PSQVIFCNRS PRVVLPVWLN FDGEPQPYPT LPPGTGRRIH SYRVYTLKER CLQVVRSLVK PENYRRLDIV RSLYEDLEDH PNVQKDLERL TQERIAHQRM GD

Attributs du produit: Human VHL full-length ORF ( ENSP00000344757, 1 a.a. - 172 a.a.) recombinant protein with GST-tag at N-terminal.

Purification: in vitro wheat germ expression system

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

Preparation method: in vitro, wheat germ expression system
Product Quality tested by: 12.5% SDS-PAGE Stained with Coomassie Blue.

Restrictions: For Research Use only

Stockage

Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH =8.0 in the elution buffer.

Conseil sur la manipulation: Aliquot to avoid repeated freezing and thawing.

Stock: -80 °C

Stockage commentaire: Best use within three months from the date of receipt of this protein.

Référence

Kim, Lee, Jang, Yi, Kim, Han, Lee, Tong, Vincelette, Gao, Yin, Evans, Choi, Qin, Liu, Zhang, Deng, Jen, Zhang, Wang, Lou: "WSB1 promotes tumor metastasis by inducing pVHL degradation." dans: Genes & development, Vol. 29, Issue 21, pp. 2244-57, (2015) (PubMed).

Détail du antigène

Antigène: VHL (Von Hippel-Lindau Tumor Suppressor, E3 Ubiquitin Protein Ligase (VHL))

Autre désignation: VHL (VHL Produits)

Synonymes: HRCA1 Protein, RCA1 Protein, VHL1 Protein, pVHL Protein, BcDNA:RH61560 Protein, CG13221 Protein, DVhl Protein, Dmel\\CG13221 Protein, Dvhl Protein, VHL Protein, d-VHL Protein, d-vhl Protein, dVHL Protein, dmVHL Protein, vhl Protein, rca1 Protein, vhl1 Protein, hrca1 Protein, zgc:158722 Protein, Vhlh Protein, von Hippel-Lindau tumor suppressor Protein, von Hippel-Lindau Protein, von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase Protein, von Hippel-Lindau disease tumor suppressor Protein, VHL Protein, Vhl Protein, vhl Protein, CpipJ_CPIJ009992 Protein

Sujet: Full Gene Name: von Hippel-Lindau tumor suppressor
Synonyms: HRCA1,RCA1,VHL1

ID gène: 7428

Pathways: Tube Formation, Signaling Events mediated by VEGFR1 and VEGFR2, Ubiquitin Proteasome Pathway