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IGSF11 Protein (AA 23-241) (Fc Tag)

IGSF11 Origine: Humain Hôte: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
N° du produit ABIN6938885
  • Antigène Voir toutes IGSF11 Protéines
    IGSF11 (Immunoglobulin Superfamily, Member 11 (IGSF11))
    Type de proteíne
    Recombinant
    Activité biologique
    Active
    Attributs du protein
    AA 23-241
    Origine
    • 10
    • 4
    • 1
    • 1
    Humain
    Source
    • 6
    • 4
    • 3
    • 2
    • 1
    HEK-293 Cells
    Purification/Conjugué
    Cette IGSF11 protéine est marqué à la Fc Tag.
    Pureté
    >95 % as determined by SDS-PAGE.
    niveau d'endotoxine
    Less than 1.0 EU per μg by the LAL method.
    Top Product
    Discover our top product IGSF11 Protéine
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    Tris with Glycine, Arginine and NaCl,  pH 7.5
    Stock
    -20 °C
  • Antigène
    IGSF11 (Immunoglobulin Superfamily, Member 11 (IGSF11))
    Autre désignation
    VSIG3 (IGSF11 Produits)
    Synonymes
    sc:d812 Protein, seurat Protein, BT-IgSF Protein, CT119 Protein, CXADRL1 Protein, Igsf13 Protein, VSIG3 Protein, 1700025L02Rik Protein, immunoglobulin superfamily member 11 Protein, immunoglobulin superfamily member 11 L homeolog Protein, immunoglobulin superfamily, member 11 Protein, IGSF11 Protein, igsf11 Protein, igsf11.L Protein, Igsf11 Protein
    Sujet
    VSIG3, also known as IGSF11, BT-IgSF, and CLMP, is a homophilic adhesion molecule that preferentially expressed in the brain. The function of VSIG3 is to stimulate cell growth through homophilic interactions. In clinical, the VSIG3 has been reported to as a novel target for cancer immunotherapy of gastrointestinal and hepatocellular carcinomas. In addition, VSIG-3 is also a ligand of B7 family member VISTA/PD-1H and inhibits human T-cell functions through a novel VSIG-3/VISTA pathway. VSIG-3/VISTA co-inhibitory pathway may provide new strategies for the treatment of human cancers and autoimmune disorders.
    Poids moléculaire
    49.7 kDa
    NCBI Accession
    NP_001015887
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