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SARS-CoV-2 Spike Protein (N501Y, RBD) (Fc Tag)

Origine: SARS Coronavirus-2 (SARS-CoV-2) Hôte: HEK-293 Cells Recombinant
N° du produit ABIN6961042
  • Antigène Voir toutes SARS-CoV-2 Spike Protéines
    SARS-CoV-2 Spike
    Type de proteíne
    Recombinant
    Attributs du protein
    N501Y, RBD
    Origine
    • 223
    • 37
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    SARS Coronavirus-2 (SARS-CoV-2)
    Source
    • 198
    • 7
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    HEK-293 Cells
    Purification/Conjugué
    Cette SARS-CoV-2 Spike protéine est marqué à la Fc Tag.
    Fonction
    SARS-CoV-2 Spike Protein RBD (Mammalian, N501Y, C-Fc)
    Attributs du produit
    Recombinant 2019-nCoV S-RBD is produced by Mammalian expression system and the target gene encoding Arg319-Ser541(N501Y) is expressed with a Fc tag at the C-terminus.
    Top Product
    Discover our top product SARS-CoV-2 Spike Protéine
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Supplied as a 0.2 μm filtered solution of PBS, pH 7.4.
  • Antigène
    SARS-CoV-2 Spike
    Autre désignation
    SARS-CoV-2 S Protein (SARS-CoV-2 Spike Produits)
    Synonymes
    E2 Protein, E2 glycoprotein precursor Protein, Surface Glycoprotein Protein, S Protein
    Classe de substances
    Viral Protein
    Sujet
    The spike (S) glycoprotein of coronaviruses is known to be essential in the binding of the virus to the host cell during the initial stages of the infection process. The SARS-CoV-2 Spike Protein mediates the membrane fusion required for virus entry and cell fusion. It is also a major immunogen and a target for entry inhibitors. SARS-CoV-2 infects the human respiratory epithelial cells through interaction with the human ACE2 receptor. The Spike Protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion. The Spike Protein plays key a part in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.
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