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CD11b Protein (Fc Tag)

ITGAM Origine: Humain Hôte: HEK-293 Cells Recombinant
N° du produit ABIN6964128
  • Antigène Voir toutes CD11b (ITGAM) Protéines
    CD11b (ITGAM) (Integrin alpha M (ITGAM))
    Type de proteíne
    Recombinant
    Origine
    • 10
    • 4
    • 4
    • 1
    Humain
    Source
    • 10
    • 4
    • 1
    • 1
    • 1
    • 1
    HEK-293 Cells
    Purification/Conjugué
    Cette CD11b protéine est marqué à la Fc Tag.
    Séquence
    ITGAM(Phe17-Asn1104)+hFc(Glu99-Ala330)
    Attributs du produit
    Tagged Protein: C-Human Fc tag
    Purification
    affinity purification
    Top Product
    Discover our top product ITGAM Protéine
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Reconstitute with deionized water
    Buffer
    Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
    Agent conservateur
    Without preservative
    Stock
    -80 °C
    Stockage commentaire
    Store at -80°C for 12 months (Avoid repeated freezing and thawing)
    Date de péremption
    12 months
  • Antigène
    CD11b (ITGAM) (Integrin alpha M (ITGAM))
    Autre désignation
    ITGAM (ITGAM Produits)
    Synonymes
    CD11b/CD18 Protein, CR3 Protein, CR3A Protein, Cd11b Protein, F730045J24Rik Protein, Ly-40 Protein, MAC1 Protein, Mac-1 Protein, Mac-1a Protein, CD11B Protein, MAC-1 Protein, MAC1A Protein, MO1A Protein, SLEB6 Protein, C3bi Protein, integrin subunit alpha M Protein, integrin alpha M Protein, integrin, alpha M (complement component 3 receptor 3 subunit) Protein, integrin alpha-M Protein, ITGAM Protein, Itgam Protein, LOC100351865 Protein
    Sujet
    Synonymes: CD11B, CR3A, MAC-1, MAC1A, MO1A, SLEB6
    Description: This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene.
    Poids moléculaire
    145.2 kDa
    UniProt
    P11215
    Pathways
    Apoptose, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation
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