IL7R Protein (Fc Tag)
-
- Antigène Voir toutes IL7R Protéines
- IL7R (Interleukin 7 Receptor (IL7R))
- Type de proteíne
- Recombinant
-
Origine
- Humain
-
Source
- HEK-293 Cells
- Purification/Conjugué
- Cette IL7R protéine est marqué à la Fc Tag.
- Fonction
- Recombinant Human IL7RA with C-terminal human Fc tag
- Specificité
- IL7RA (Glu21-Gly236) hFc (Glu99-Ala330)
- Attributs du produit
- Extracellular Domain Protein
- Purification
- affinity purification
- Pureté
- The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
- Top Product
- Discover our top product IL7R Protéine
-
-
- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Reconstitution
- Reconstitute with deionized water
- Buffer
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- Agent conservateur
- Without preservative
- Stock
- -20 °C,-80 °C
- Stockage commentaire
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Date de péremption
- 12 months
-
- Antigène
- IL7R (Interleukin 7 Receptor (IL7R))
- Autre désignation
- IL7RA (IL7R Produits)
- Synonymes
- IL7R Protein, CD127 Protein, IL-7Ralpha Protein, CDW127 Protein, IL-7R-alpha Protein, IL7RA Protein, ILRA Protein, IL-7RA Protein, interleukin 7 receptor Protein, IL7R Protein, Il7r Protein
- Sujet
-
Synonymes: CD127, CDW127, IL-7R-alpha, IL7RA, ILRA
Description: The protein encoded by this gene is a receptor for interleukin 7 (IL7). The function of this receptor requires the interleukin 2 receptor, gamma chain (IL2RG), which is a common gamma chain shared by the receptors of various cytokines, including interleukins 2, 4, 7, 9, and 15. This protein has been shown to play a critical role in V(D)J recombination during lymphocyte development. Defects in this gene may be associated with severe combined immunodeficiency (SCID). Alternatively spliced transcript variants have been found. - Poids moléculaire
- predicted molecular mass of 51.0 kDa after removal of the signal peptide.The apparent molecular mass of IL7RA-hFc is 55-100 kDa due to glycosylation.
- UniProt
- P16871
- Pathways
- Signalistation JAK/STAT, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Regulation of Cell Size
-