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KIR2DL2 Protein (Fc Tag)

KIR2DL2 Origine: Humain Hôte: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
N° du produit ABIN6964164
  • Antigène Voir toutes KIR2DL2 Protéines
    KIR2DL2 (Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 2 (KIR2DL2))
    Type de proteíne
    Recombinant
    Origine
    Humain
    Source
    • 3
    • 2
    • 1
    HEK-293 Cells
    Purification/Conjugué
    Cette KIR2DL2 protéine est marqué à la Fc Tag.
    Fonction
    Recombinant Human KIR2DL2 Protein with C-terminal human Fc tag
    Specificité
    KIR2DL2 (His22-His245) hFc (Glu99-Ala330)
    Attributs du produit
    Extracellular Domain Protein
    Purification
    affinity purification
    Pureté
    The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
    Top Product
    Discover our top product KIR2DL2 Protéine
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Reconstitute with deionized water
    Buffer
    Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
    Agent conservateur
    Without preservative
    Stock
    -20 °C,-80 °C
    Stockage commentaire
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    Date de péremption
    12 months
  • Antigène
    KIR2DL2 (Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 2 (KIR2DL2))
    Autre désignation
    KIR2DL2 (KIR2DL2 Produits)
    Synonymes
    NKAT6 Protein, p58.2 Protein, CD158b Protein, CD158B1 Protein, killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 2 Protein, KIR2DL2 Protein
    Sujet
    Synonymes: CD158b, CD158B1, NKAT-6, NKAT6, p58.2
    Description: Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies among haplotypes, although several "framework" genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2). The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short cytoplasmic domain lack the ITIM motif and instead associate with the TYRO protein tyrosine kinase binding protein to transduce activating signals. The ligands for several KIR proteins are subsets of HLA class I molecules
    Poids moléculaire
    predicted molecular mass of 50.7 kDa after removal of the signal peptide.The apparent molecular mass of KIR2DL2-hFc is 55-100 kDa due to glycosylation.
    UniProt
    P43627
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