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CRLF2 Protein (Fc Tag)

CRLF2 Origine: Humain Hôte: HEK-293 Cells Recombinant
N° du produit ABIN6964184
  • Antigène Voir toutes CRLF2 Protéines
    CRLF2 (Cytokine Receptor-Like Factor 2 (CRLF2))
    Type de proteíne
    Recombinant
    Origine
    • 12
    • 8
    • 1
    • 1
    Humain
    Source
    • 6
    • 5
    • 5
    • 3
    • 1
    • 1
    • 1
    HEK-293 Cells
    Purification/Conjugué
    Cette CRLF2 protéine est marqué à la Fc Tag.
    Séquence
    CRLF2(Gln23-Lys231)+hFc(Glu99-Ala330)
    Attributs du produit
    Tagged Protein: C-Human Fc tag
    Purification
    affinity purification
    Top Product
    Discover our top product CRLF2 Protéine
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Reconstitute with deionized water
    Buffer
    Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
    Agent conservateur
    Without preservative
    Stock
    -80 °C
    Stockage commentaire
    Store at -80°C for 12 months (Avoid repeated freezing and thawing)
    Date de péremption
    12 months
  • Antigène
    CRLF2 (Cytokine Receptor-Like Factor 2 (CRLF2))
    Autre désignation
    CRLF2 (CRLF2 Produits)
    Synonymes
    CRLF2 Protein, CRL2 Protein, CRLF2Y Protein, TSLPR Protein, CRLM2 Protein, Ly114 Protein, Tpte2 Protein, Tslpr Protein, Crl2 Protein, cytokine receptor like factor 2 Protein, cytokine receptor-like factor 2 Protein, CRLF2 Protein, Crlf2 Protein
    Sujet
    Synonymes: CRL2, CRLF2Y, TSLPR
    Description: This gene encodes a member of the type I cytokine receptor family. The encoded protein is a receptor for thymic stromal lymphopoietin (TSLP). Together with the interleukin 7 receptor (IL7R), the encoded protein and TSLP activate STAT3, STAT5, and JAK2 pathways, which control processes such as cell proliferation and development of the hematopoietic system. Rearrangement of this gene with immunoglobulin heavy chain gene (IGH) on chromosome 14, or with P2Y purinoceptor 8 gene (P2RY8) on the same X or Y chromosomes is associated with B-progenitor acute lymphoblastic leukemia (ALL) and Down syndrome ALL. Alternatively spliced transcript variants have been found for this gene.
    Poids moléculaire
    48.51 kDa
    UniProt
    Q9HC73
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