K-RAS Protein (Fc Tag)

N° du produit ABIN6964285

Détail du produit

Antigène: K-RAS (KRAS) (GTPase Kras (KRAS))

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette K-RAS protéine est marqué à la Fc Tag.

Fonction: Recombinant Human KRAS with C-terminal human Fc tag

Specificité: KRAS (Thr2-Cys185) hFc (Glu99-Ala330)

Attributs du produit: Extracellular Domain Protein

Purification: affinity purification

Pureté: The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Reconstitute with deionized water

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Agent conservateur: Without preservative

Stock: -20 °C,-80 °C

Stockage commentaire: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Date de péremption: 12 months

Détail du antigène

Antigène: K-RAS (KRAS) (GTPase Kras (KRAS))

Autre désignation: KRAS (KRAS Produits)

Synonymes: wu:fa04e08 Protein, wu:fc14b12 Protein, wu:fc23g10 Protein, wu:fj89d12 Protein, zgc:85725 Protein, Kras2 Protein, c-Ki-ras Protein, p21 Protein, C-K-RAS Protein, CFC2 Protein, K-RAS2A Protein, K-RAS2B Protein, K-RAS4A Protein, K-RAS4B Protein, KI-RAS Protein, KRAS1 Protein, KRAS2 Protein, NS Protein, NS3 Protein, RASK2 Protein, AI929937 Protein, K-ras Protein, Ki-ras Protein, Kras-2 Protein, p21B Protein, ras Protein, k-ras Protein, kras Protein, kras-a Protein, kras-b Protein, rask2 Protein, K-RAS Protein, p21ras Protein, KRAS proto-oncogene, GTPase Protein, v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog Protein, Kirsten rat sarcoma viral oncogene homolog Protein, semicolonial-7 Protein, Ras family protein Protein, GTPase KRas Protein, Kirsten rat sarcoma viral oncogene homolog S homeolog Protein, KRAS Protein, kras Protein, Kras Protein, smco-7 Protein, PGTG_03066 Protein, Tsp_02666 Protein, Tsp_01642 Protein, rask Protein, kras.S Protein

Classe de substances: Viral Protein

Sujet: Synonymes: C-K-RAS, c-Ki-ras2, CFC2, K-Ras, K-RAS2A, K-RAS2B, K-RAS4A, K-RAS4B, KI-RAS, KRAS1, KRAS2, NS, NS3, RALD, RASK2
Description: This gene, a Kirsten ras oncogene homolog from the mammalian ras gene family, encodes a protein that is a member of the small GTPase superfamily. A single amino acid substitution is responsible for an activating mutation. The transforming protein that results is implicated in various malignancies, including lung adenocarcinoma, mucinous adenoma, ductal carcinoma of the pancreas and colorectal carcinoma. Alternative splicing leads to variants encoding two isoforms that differ in the C-terminal region. [provided by RefSeq, Jul 2008]

Poids moléculaire: predicted molecular mass of 47.1 kDa after removal of the signal peptide. The apparent molecular mass of KRAS-hFc is 35-55 kDa due to glycosylation.

UniProt: P01116