DKK2 Protein (Fc Tag)
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- Antigène Voir toutes DKK2 Protéines
- DKK2 (Dickkopf 2 Homolog (DKK2))
- Type de proteíne
- Recombinant
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Origine
- Humain
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Source
- HEK-293 Cells
- Purification/Conjugué
- Cette DKK2 protéine est marqué à la Fc Tag.
- Fonction
- Recombinant Human DKK2 with C-terminal human Fc tag
- Specificité
- DKK2 (Lys34-Ile259) hFc (Glu99-Ala330)
- Attributs du produit
- Extracellular Domain Protein
- Purification
- affinity purification
- Pureté
- The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
- Top Product
- Discover our top product DKK2 Protéine
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Reconstitute with deionized water
- Buffer
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- Agent conservateur
- Without preservative
- Stock
- -20 °C,-80 °C
- Stockage commentaire
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Date de péremption
- 12 months
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- Antigène
- DKK2 (Dickkopf 2 Homolog (DKK2))
- Autre désignation
- DKK2 (DKK2 Produits)
- Synonymes
- DKK-2 Protein, Dkk4 Protein, zgc:171574 Protein, dickkopf WNT signaling pathway inhibitor 2 Protein, DKK2 Protein, Dkk2 Protein, dkk2 Protein
- Sujet
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Synonymes: DKK-2
Description: This gene encodes a protein that is a member of the dickkopf family. The secreted protein contains two cysteine rich regions and is involved in embryonic development through its interactions with the Wnt signaling pathway. It can act as either an agonist or antagonist of Wnt/beta-catenin signaling, depending on the cellular context and the presence of the co-factor kremen 2. Activity of this protein is also modulated by binding to the Wnt co-receptor LDL-receptor related protein 6 (LRP6). [provided by RefSeq, Jul 2008] - Poids moléculaire
- predicted molecular mass of 51.2 kDa after removal of the signal peptide. The apparent molecular mass of DKK2-hFc is 55-70 kDa due to glycosylation.
- UniProt
- Q9UBU2
- Pathways
- Signalisation WNT
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