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DKK2 Protein (Fc Tag)

DKK2 Origine: Humain Hôte: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
N° du produit ABIN6964354
  • Antigène Voir toutes DKK2 Protéines
    DKK2 (Dickkopf 2 Homolog (DKK2))
    Type de proteíne
    Recombinant
    Origine
    • 9
    • 1
    Humain
    Source
    • 5
    • 2
    • 2
    • 1
    HEK-293 Cells
    Purification/Conjugué
    Cette DKK2 protéine est marqué à la Fc Tag.
    Fonction
    Recombinant Human DKK2 with C-terminal human Fc tag
    Specificité
    DKK2 (Lys34-Ile259) hFc (Glu99-Ala330)
    Attributs du produit
    Extracellular Domain Protein
    Purification
    affinity purification
    Pureté
    The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
    Top Product
    Discover our top product DKK2 Protéine
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Reconstitute with deionized water
    Buffer
    Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
    Agent conservateur
    Without preservative
    Stock
    -20 °C,-80 °C
    Stockage commentaire
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    Date de péremption
    12 months
  • Antigène
    DKK2 (Dickkopf 2 Homolog (DKK2))
    Autre désignation
    DKK2 (DKK2 Produits)
    Synonymes
    DKK-2 Protein, Dkk4 Protein, zgc:171574 Protein, dickkopf WNT signaling pathway inhibitor 2 Protein, DKK2 Protein, Dkk2 Protein, dkk2 Protein
    Sujet
    Synonymes: DKK-2
    Description: This gene encodes a protein that is a member of the dickkopf family. The secreted protein contains two cysteine rich regions and is involved in embryonic development through its interactions with the Wnt signaling pathway. It can act as either an agonist or antagonist of Wnt/beta-catenin signaling, depending on the cellular context and the presence of the co-factor kremen 2. Activity of this protein is also modulated by binding to the Wnt co-receptor LDL-receptor related protein 6 (LRP6). [provided by RefSeq, Jul 2008]
    Poids moléculaire
    predicted molecular mass of 51.2 kDa after removal of the signal peptide. The apparent molecular mass of DKK2-hFc is 55-70 kDa due to glycosylation.
    UniProt
    Q9UBU2
    Pathways
    Signalisation WNT
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