CD8 Protein (CD8) (AA 22-182) (His tag,FITC)

N° du produit ABIN6973025

Détail du produit

Antigène: CD8

Type de proteíne: Recombinant

Activité biologique: Active

Attributs du protein: AA 22-182

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette CD8 protéine est marqué à la His tag,FITC.

Attributs du produit: FITC-Labeled Human CD8 alpha&beta (CD8A&CD8B) Heterodimer Protein, His Tag&Tag Free

Pureté: >90 % as determined by SDS-PAGE.

niveau d'endotoxine: Less than 1.0 EU per μg by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: PBS, pH 7.4

Stock: -20 °C

Détail du antigène

Antigène: CD8

Autre désignation: CD8 alpha & beta (CD8 Produits)

Synonymes: CD8 Protein, Leu2 Protein, MAL Protein, p32 Protein, CD8a molecule Protein, CD8A Protein

Sujet: Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. CD8A forms disulfide-linked heterodimers with CD8B at the cell surface. CD8A homodimer molecules also promote the survival and differentiation of activated lymphocytes into memory CD8 T-cells. Additionally, CD8B plays a critical role in thymic selection of CD8+ T-cells. A palmitoylation site in the cytoplasmic tail of CD8B chain contributes to partitioning of CD8 into the plasma membrane lipid rafts where signaling proteins are enriched.

Poids moléculaire: 19.5 kDa (CD8A) & 22.1 kDa (CD8B)