SARS-CoV-2 Spike Protein (B.1.617.1 - kappa) (rho-1D4 tag)

N° du produit ABIN6976302

Détail du produit

Highlights:

• Recombinant trimeric S protein of the SARS-CoV-2 variant of concern B.1.617.
• Contains E154K, L452R, E484Q, D614G, and P681R mutations characteristic for the SARS-CoV-2 kappa variant (B.1.617.1).

Antigène: SARS-CoV-2 Spike

Type de proteíne: Recombinant

Attributs du protein: B.1.617.1 - kappa

Origine: SARS Coronavirus-2 (SARS-CoV-2), SARS CoV-2 Kappa

Source: HEK-293 Cells

Purification/Conjugué: Cette SARS-CoV-2 Spike protéine est marqué à la rho-1D4 tag.

Application: ELISA, Ligand Binding Assay (LBA)

Fonction: This is the spike protein of the mutant strain B.1.617, also commonly known as the "India" or "Kappa mutant".

Séquence: 1286 amino acids (including Rho1D4 tag and linker)

Specificité: Mutation that differ from "original" SPIKE protein: G142D, E154K, L452R, E484Q, D614G, P681R, Q1071H

Attributs du produit: "SARS CoV-2 full-length Spike B.1.617 Mutation"
All viruses undergo fast mutations and adept quickly to the countermeasures that the immune systems creates against them. SARS-CoV-2 of the COVID-19 pandemic is no exception here. During the pandemic multiple mutant strains arose. To help the science combat these mutants we offer these mutant SPIKE proteins.
We offer the SPIKE protein of the mutants in full-length and active in their native trimeric form, stabilized with the LMNG detergent.

Pureté: > 98% as determined by SDS-PAGE

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

Further modifications:
- furin cleavage site "682-RRAR|SV-687" mutated to "682-GSAG|PP-687"
- C-terminal Rho1D4 tag fused with spacer "GSSG" to protein sequence
Size: 1286 amino acids (including Rho1D4 tag and linker)

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: 20 mM Hepes pH 7.5, 150 mM NaCl, 0.001 % LMNG

Stock: -80 °C

Stockage commentaire: Store at -80°C. Avoid freeze-thaw cycles

Détail du antigène

Antigène: SARS-CoV-2 Spike

Autre désignation: SARS2 Spike glycoprotein (SARS-CoV-2 Spike Produits)

Synonymes: E2 Protein, E2 glycoprotein precursor Protein, Surface Glycoprotein Protein, S Protein

Classe de substances: Viral Protein

Sujet: All viruses undergo fast mutations and adapt quickly to the countermeasures that the immune systems creates. SARS-CoV-2 of the COVID-19 pandemic is no exception to this. During the pandemic multiple mutant strains arose.

Poids moléculaire: 142190.43 Da

UniProt: P0DTC2