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LY75/DEC-205 Protein (AA 28-1666) (His tag)

LY75 Origine: Humain Hôte: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE.
N° du produit ABIN6992338
  • Antigène Voir toutes LY75/DEC-205 (LY75) Protéines
    LY75/DEC-205 (LY75) (Lymphocyte Antigen 75 (LY75))
    Type de proteíne
    Recombinant
    Attributs du protein
    AA 28-1666
    Origine
    • 4
    • 3
    • 1
    Humain
    Source
    • 3
    • 3
    • 2
    HEK-293 Cells
    Purification/Conjugué
    Cette LY75/DEC-205 protéine est marqué à la His tag.
    Fonction
    Human LY75 / CD205 Protein, His Tag
    Pureté
    >90 % as determined by SDS-PAGE.
    niveau d'endotoxine
    Less than 1.0 EU per μg by the LAL method.
    Top Product
    Discover our top product LY75 Protéine
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    PBS, pH 7.4
    Stock
    -20 °C
  • Antigène
    LY75/DEC-205 (LY75) (Lymphocyte Antigen 75 (LY75))
    Autre désignation
    LY75 (LY75 Produits)
    Synonymes
    LY75 Protein, MGC140308 Protein, DEC205 Protein, im:7150926 Protein, si:dkey-78p20.2 Protein, LYT75 Protein, CD205 Protein, DEC-205 Protein, CLEC13B Protein, GP200-MR6 Protein, LY-75 Protein, RGD1565962 Protein, Ly-75 Protein, lymphocyte antigen 75 Protein, CD205 protein Protein, CD302 antigen Protein, LY75 Protein, Cyan7822_2917 Protein, LY5 Protein, ly75 Protein, cd205 Protein, LOC100380704 Protein, LOC100433861 Protein, LOC100483541 Protein, Ly75 Protein
    Sujet
    Lymphocyte antigen 75 (Ly 75, also known as CD205, CLEC13B, GP200-MR6 and DEC-205, is a type I transmembrane protein that is primarily expressed on dendritic cells and thymic epithelial cells. LY75 functions as an endocytic receptor for antigens. MEN1309/OBT076, the first antibody drug targeting CD205, has shown strong preclinical anti-tumor activity in lymphoma. After being verified as a single drug in vivo, the antibody-drug conjugate has a synergistic effect with the BCL2 inhibitor Venetoclax and the anti-cd20 monoclonal antibody rituximab.
    Poids moléculaire
    190.7 kDa
    NCBI Accession
    NP_002340
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