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SARS-CoV-2 Spike Protein (N501Y, RBD) (His tag)

Origine: SARS Coronavirus-2 (SARS-CoV-2) Hôte: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
N° du produit ABIN7013267
  • Antigène Voir toutes SARS-CoV-2 Spike Protéines
    SARS-CoV-2 Spike
    Type de proteíne
    Recombinant
    Activité biologique
    Active
    Attributs du protein
    N501Y, RBD
    Origine
    • 223
    • 37
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    SARS Coronavirus-2 (SARS-CoV-2)
    Source
    • 198
    • 7
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    HEK-293 Cells
    Purification/Conjugué
    Cette SARS-CoV-2 Spike protéine est marqué à la His tag.
    Séquence
    AA 319-537
    Specificité
    SARS-CoV-2 (COVID-19) S protein RBD (N501Y), His Tag (MALS verified)
    Attributs du produit
    SARS-CoV-2 S protein RBD (N501Y), His Tag is expressed from human 293 cells (HEK293). It contains AA Arg 319 - Lys 537 (Accession # QHD43416.1(N501Y). N501Y mutaion was identified in both the SARS-CoV-2 variant (known as 20B/501Y.V1, VOC 202012/01, or B.1.1.7 lineage) which emerged in the United Kindom and SARS-CoV-2 variant (known as 20C/501Y.V2 or B.1.351 lineage) which emerged in South Africa.
    Pureté
    >95 % as determined by SDS-PAGE.
    niveau d'endotoxine
    Less than 1.0 EU per μg by the LAL method.
    Top Product
    Discover our top product SARS-CoV-2 Spike Protéine
  • Indications d'application
    MALS verified
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    PBS, pH 7.4
    Stock
    -20 °C
  • Longworth, Dittmar: "An antigen microarray protocol for COVID-19 serological analysis." dans: STAR protocols, Vol. 2, Issue 3, pp. 100815, (2021) (PubMed).

  • Antigène
    SARS-CoV-2 Spike
    Autre désignation
    SARS-CoV-2 S protein (SARS-CoV-2 Spike Produits)
    Synonymes
    E2 Protein, E2 glycoprotein precursor Protein, Surface Glycoprotein Protein, S Protein
    Classe de substances
    Viral Protein
    Sujet
    It's been reported that SARS-CoV-2 can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.
    Poids moléculaire
    26.6 kDa
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